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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3B
All Species:
14.24
Human Site:
S295
Identified Species:
26.11
UniProt:
O75182
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75182
NP_056075.1
1162
133066
S295
L
R
G
T
K
D
L
S
I
A
A
V
G
K
Y
Chimpanzee
Pan troglodytes
XP_512485
1159
132821
S292
L
R
G
T
K
D
L
S
I
A
A
V
G
K
Y
Rhesus Macaque
Macaca mulatta
XP_001103619
1210
138821
T329
S
S
V
L
L
S
K
T
T
A
E
K
V
D
S
Dog
Lupus familis
XP_852728
1090
125608
E287
R
R
V
L
K
S
Q
E
V
Y
E
N
F
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q62141
1098
126387
A289
T
K
D
L
S
I
A
A
V
G
K
Y
G
T
L
Rat
Rattus norvegicus
NP_001102231
1129
127784
G291
T
P
V
T
I
S
L
G
T
A
P
S
L
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511618
1116
128787
S289
L
R
G
T
K
D
L
S
V
A
T
V
G
K
Y
Chicken
Gallus gallus
XP_418257
1273
146269
S446
L
R
G
T
K
D
L
S
V
A
T
V
G
K
Y
Frog
Xenopus laevis
NP_001090601
1125
130319
A297
K
S
K
D
Q
S
M
A
S
V
G
K
Y
G
T
Zebra Danio
Brachydanio rerio
NP_001038410
1196
136639
E301
S
L
P
L
K
K
V
E
E
E
E
L
N
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
R434
N
L
S
S
I
L
V
R
S
E
H
S
E
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48686
1353
153834
S311
K
G
A
M
K
S
Y
S
Q
D
L
A
I
V
D
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
L541
R
G
I
P
Q
Q
N
L
P
P
I
G
S
F
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.9
89.9
N.A.
87.6
50.9
N.A.
85.8
77.4
71.4
63.9
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
99.5
66.7
91.9
N.A.
91.3
64
N.A.
91
82.4
82.1
76
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
20
N.A.
86.6
86.6
0
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
13.3
20
N.A.
26.6
26.6
N.A.
93.3
93.3
20
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
16
0
47
16
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
31
0
0
0
8
0
0
0
8
8
% D
% Glu:
0
0
0
0
0
0
0
16
8
16
24
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
0
16
31
0
0
0
0
8
0
8
8
8
39
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
0
16
8
0
0
16
0
8
0
8
0
0
% I
% Lys:
16
8
8
0
54
8
8
0
0
0
8
16
0
39
8
% K
% Leu:
31
16
0
31
8
8
39
8
0
0
8
8
8
8
8
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
8
8
0
8
% N
% Pro:
0
8
8
8
0
0
0
0
8
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
16
8
8
0
8
0
0
0
0
8
8
% Q
% Arg:
16
39
0
0
0
0
0
8
0
0
0
0
0
0
8
% R
% Ser:
16
16
8
8
8
39
0
39
16
0
0
16
8
0
16
% S
% Thr:
16
0
0
39
0
0
0
8
16
0
16
0
0
16
8
% T
% Val:
0
0
24
0
0
0
16
0
31
8
0
31
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
8
0
8
8
0
31
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _