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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3B
All Species:
6.36
Human Site:
S558
Identified Species:
11.67
UniProt:
O75182
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75182
NP_056075.1
1162
133066
S558
K
A
P
E
I
I
E
S
L
K
K
N
P
V
T
Chimpanzee
Pan troglodytes
XP_512485
1159
132821
S555
K
A
P
E
I
I
E
S
L
K
K
N
P
V
T
Rhesus Macaque
Macaca mulatta
XP_001103619
1210
138821
G620
K
A
A
D
I
I
D
G
L
R
K
N
P
S
I
Dog
Lupus familis
XP_852728
1090
125608
F544
L
D
H
Q
A
V
N
F
K
Q
N
D
T
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q62141
1098
126387
F547
W
R
E
A
Q
Q
G
F
N
K
I
W
R
E
Q
Rat
Rattus norvegicus
NP_001102231
1129
127784
S565
S
Y
R
A
L
P
K
S
Y
Q
Q
P
K
C
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511618
1116
128787
Q547
E
E
E
W
R
E
A
Q
Q
G
F
N
K
I
W
Chicken
Gallus gallus
XP_418257
1273
146269
Q704
E
E
E
W
R
E
A
Q
Q
G
F
N
K
I
W
Frog
Xenopus laevis
NP_001090601
1125
130319
N558
R
E
A
Q
R
G
F
N
K
I
W
R
E
Q
Y
Zebra Danio
Brachydanio rerio
NP_001038410
1196
136639
G570
K
A
P
E
I
I
E
G
L
K
R
S
P
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
G710
K
A
A
D
I
I
E
G
L
K
K
N
P
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48686
1353
153834
V578
H
G
L
D
V
M
D
V
L
K
K
N
V
S
L
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
D881
E
R
G
F
E
I
I
D
A
L
H
E
H
P
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.9
89.9
N.A.
87.6
50.9
N.A.
85.8
77.4
71.4
63.9
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
99.5
66.7
91.9
N.A.
91.3
64
N.A.
91
82.4
82.1
76
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
53.3
0
N.A.
6.6
13.3
N.A.
6.6
6.6
0
73.3
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
73.3
26.6
N.A.
6.6
40
N.A.
20
20
20
86.6
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
24
16
8
0
16
0
8
0
0
0
0
16
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
24
0
0
16
8
0
0
0
8
0
0
0
% D
% Glu:
24
24
24
24
8
16
31
0
0
0
0
8
8
8
0
% E
% Phe:
0
0
0
8
0
0
8
16
0
0
16
0
0
0
0
% F
% Gly:
0
8
8
0
0
8
8
24
0
16
0
0
0
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
0
0
0
0
39
47
8
0
0
8
8
0
0
16
8
% I
% Lys:
39
0
0
0
0
0
8
0
16
47
39
0
24
8
0
% K
% Leu:
8
0
8
0
8
0
0
0
47
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
8
0
8
54
0
0
0
% N
% Pro:
0
0
24
0
0
8
0
0
0
0
0
8
39
8
0
% P
% Gln:
0
0
0
16
8
8
0
16
16
16
8
0
0
8
8
% Q
% Arg:
8
16
8
0
24
0
0
0
0
8
8
8
8
0
0
% R
% Ser:
8
0
0
0
0
0
0
24
0
0
0
8
0
16
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
31
% T
% Val:
0
0
0
0
8
8
0
8
0
0
0
0
8
16
8
% V
% Trp:
8
0
0
16
0
0
0
0
0
0
8
8
0
0
16
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _