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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3B
All Species:
4.55
Human Site:
S739
Identified Species:
8.33
UniProt:
O75182
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75182
NP_056075.1
1162
133066
S739
K
P
A
P
G
P
H
S
S
P
P
E
E
K
G
Chimpanzee
Pan troglodytes
XP_512485
1159
132821
S736
K
P
A
P
G
P
H
S
S
P
P
E
E
K
G
Rhesus Macaque
Macaca mulatta
XP_001103619
1210
138821
G786
M
D
V
D
E
A
T
G
A
V
K
K
H
N
G
Dog
Lupus familis
XP_852728
1090
125608
N709
S
L
F
F
A
N
N
N
W
Y
F
F
L
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q62141
1098
126387
F712
L
D
D
V
Y
S
L
F
F
A
N
N
N
W
Y
Rat
Rattus norvegicus
NP_001102231
1129
127784
L730
E
K
Y
Y
L
K
S
L
D
H
Q
G
I
N
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511618
1116
128787
D713
E
E
K
A
G
F
C
D
A
V
A
S
E
P
Q
Chicken
Gallus gallus
XP_418257
1273
146269
D870
E
T
K
A
T
F
C
D
V
T
A
A
E
P
H
Frog
Xenopus laevis
NP_001090601
1125
130319
I723
E
P
P
P
P
E
E
I
P
H
E
P
P
P
K
Zebra Danio
Brachydanio rerio
NP_001038410
1196
136639
G762
T
G
Q
Q
Q
L
N
G
E
S
R
R
R
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
I891
T
E
T
K
K
S
K
I
P
N
G
P
L
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48686
1353
153834
H759
G
E
S
E
G
S
P
H
N
Y
A
S
V
A
D
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
M1063
K
R
P
Y
Q
Q
E
M
S
L
L
D
I
L
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.9
89.9
N.A.
87.6
50.9
N.A.
85.8
77.4
71.4
63.9
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
99.5
66.7
91.9
N.A.
91.3
64
N.A.
91
82.4
82.1
76
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
6.6
0
N.A.
0
0
N.A.
13.3
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
20
20
N.A.
0
6.6
N.A.
26.6
13.3
20
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
16
8
8
0
0
16
8
24
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
8
% C
% Asp:
0
16
8
8
0
0
0
16
8
0
0
8
0
0
8
% D
% Glu:
31
24
0
8
8
8
16
0
8
0
8
16
31
8
0
% E
% Phe:
0
0
8
8
0
16
0
8
8
0
8
8
0
0
8
% F
% Gly:
8
8
0
0
31
0
0
16
0
0
8
8
0
0
24
% G
% His:
0
0
0
0
0
0
16
8
0
16
0
0
8
0
16
% H
% Ile:
0
0
0
0
0
0
0
16
0
0
0
0
16
0
0
% I
% Lys:
24
8
16
8
8
8
8
0
0
0
8
8
0
16
16
% K
% Leu:
8
8
0
0
8
8
8
8
0
8
8
0
16
8
8
% L
% Met:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
16
8
8
8
8
8
8
16
0
% N
% Pro:
0
24
16
24
8
16
8
0
16
16
16
16
8
24
0
% P
% Gln:
0
0
8
8
16
8
0
0
0
0
8
0
0
0
8
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
8
8
8
16
0
% R
% Ser:
8
0
8
0
0
24
8
16
24
8
0
16
0
0
0
% S
% Thr:
16
8
8
0
8
0
8
0
0
8
0
0
0
0
0
% T
% Val:
0
0
8
8
0
0
0
0
8
16
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% W
% Tyr:
0
0
8
16
8
0
0
0
0
16
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _