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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3B
All Species:
14.85
Human Site:
T125
Identified Species:
27.22
UniProt:
O75182
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75182
NP_056075.1
1162
133066
T125
L
N
I
Q
S
P
L
T
S
Q
E
N
S
H
N
Chimpanzee
Pan troglodytes
XP_512485
1159
132821
T122
L
N
I
Q
S
P
L
T
S
Q
E
N
S
H
N
Rhesus Macaque
Macaca mulatta
XP_001103619
1210
138821
S156
D
I
M
K
E
F
K
S
Q
S
I
D
T
P
G
Dog
Lupus familis
XP_852728
1090
125608
V118
Y
K
E
D
K
P
Q
V
P
L
E
S
D
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q62141
1098
126387
S119
N
I
Q
S
P
L
S
S
Q
D
N
S
H
S
H
Rat
Rattus norvegicus
NP_001102231
1129
127784
L121
G
Q
Q
Q
F
Q
R
L
K
V
E
D
A
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511618
1116
128787
A119
L
N
V
Q
S
S
V
A
N
Q
E
N
S
H
N
Chicken
Gallus gallus
XP_418257
1273
146269
T276
L
S
I
Q
S
P
L
T
S
Q
E
N
S
H
N
Frog
Xenopus laevis
NP_001090601
1125
130319
S125
A
T
T
S
S
L
S
S
S
H
V
I
V
P
P
Zebra Danio
Brachydanio rerio
NP_001038410
1196
136639
S122
A
F
L
Q
S
P
F
S
S
Q
V
S
P
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
P235
S
Q
I
N
V
S
T
P
G
N
P
I
P
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48686
1353
153834
R134
F
V
N
K
I
K
T
R
F
Q
G
D
D
R
V
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
P305
D
P
I
R
V
T
T
P
M
G
T
T
T
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.9
89.9
N.A.
87.6
50.9
N.A.
85.8
77.4
71.4
63.9
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
99.5
66.7
91.9
N.A.
91.3
64
N.A.
91
82.4
82.1
76
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
0
13.3
N.A.
0
13.3
N.A.
66.6
93.3
13.3
33.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
33.3
20
N.A.
20
33.3
N.A.
86.6
100
20
53.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
8
0
0
0
0
0
8
0
24
16
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
0
0
47
0
0
0
0
% E
% Phe:
8
8
0
0
8
8
8
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
8
8
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
8
31
8
% H
% Ile:
0
16
39
0
8
0
0
0
0
0
8
16
0
0
0
% I
% Lys:
0
8
0
16
8
8
8
0
8
0
0
0
0
8
0
% K
% Leu:
31
0
8
0
0
16
24
8
0
8
0
0
0
8
8
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
24
8
8
0
0
0
0
8
8
8
31
0
0
39
% N
% Pro:
0
8
0
0
8
39
0
16
8
0
8
0
16
16
8
% P
% Gln:
0
16
16
47
0
8
8
0
16
47
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
8
8
0
0
0
0
0
8
0
% R
% Ser:
8
8
0
16
47
16
16
31
39
8
0
24
31
16
8
% S
% Thr:
0
8
8
0
0
8
24
24
0
0
8
8
16
0
0
% T
% Val:
0
8
8
0
16
0
8
8
0
8
16
0
8
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _