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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3B
All Species:
22.73
Human Site:
T192
Identified Species:
41.67
UniProt:
O75182
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75182
NP_056075.1
1162
133066
T192
S
F
L
E
I
L
H
T
Y
Q
K
E
Q
L
N
Chimpanzee
Pan troglodytes
XP_512485
1159
132821
T189
S
F
L
E
I
L
H
T
Y
Q
K
E
Q
L
N
Rhesus Macaque
Macaca mulatta
XP_001103619
1210
138821
H226
Q
P
Q
P
P
P
Q
H
P
S
Q
P
S
T
Q
Dog
Lupus familis
XP_852728
1090
125608
N184
E
V
F
T
E
V
A
N
L
F
R
G
Q
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q62141
1098
126387
Q186
L
E
I
L
H
T
Y
Q
K
E
Q
L
H
T
K
Rat
Rattus norvegicus
NP_001102231
1129
127784
P188
G
F
N
T
F
L
P
P
G
Y
K
I
E
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511618
1116
128787
T186
S
F
L
E
I
L
H
T
Y
Q
K
E
Q
L
N
Chicken
Gallus gallus
XP_418257
1273
146269
T343
S
F
L
E
I
L
H
T
Y
Q
K
E
Q
L
N
Frog
Xenopus laevis
NP_001090601
1125
130319
T194
S
F
L
E
I
L
H
T
Y
Q
K
D
Q
L
N
Zebra Danio
Brachydanio rerio
NP_001038410
1196
136639
T198
A
T
S
V
S
P
P
T
S
E
P
S
P
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
E331
G
K
E
K
K
K
I
E
F
N
H
A
I
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48686
1353
153834
A208
R
E
R
G
V
S
L
A
D
K
K
D
R
I
I
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
T438
H
F
L
E
I
L
Q
T
Y
Q
R
E
Q
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.9
89.9
N.A.
87.6
50.9
N.A.
85.8
77.4
71.4
63.9
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
99.5
66.7
91.9
N.A.
91.3
64
N.A.
91
82.4
82.1
76
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
0
6.6
N.A.
0
20
N.A.
100
100
93.3
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
6.6
26.6
N.A.
26.6
33.3
N.A.
100
100
100
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
16
0
0
8
% D
% Glu:
8
16
8
47
8
0
0
8
0
16
0
39
8
8
8
% E
% Phe:
0
54
8
0
8
0
0
0
8
8
0
0
0
0
0
% F
% Gly:
16
0
0
8
0
0
0
0
8
0
0
8
0
0
0
% G
% His:
8
0
0
0
8
0
39
8
0
0
8
0
8
0
0
% H
% Ile:
0
0
8
0
47
0
8
0
0
0
0
8
8
8
8
% I
% Lys:
0
8
0
8
8
8
0
0
8
8
54
0
0
8
8
% K
% Leu:
8
0
47
8
0
54
8
0
8
0
0
8
0
39
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
39
% N
% Pro:
0
8
0
8
8
16
16
8
8
0
8
8
8
0
8
% P
% Gln:
8
0
8
0
0
0
16
8
0
47
16
0
54
0
16
% Q
% Arg:
8
0
8
0
0
0
0
0
0
0
16
0
8
0
0
% R
% Ser:
39
0
8
0
8
8
0
0
8
8
0
8
8
0
0
% S
% Thr:
0
8
0
16
0
8
0
54
0
0
0
0
0
24
0
% T
% Val:
0
8
0
8
8
8
0
0
0
0
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
47
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _