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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3B
All Species:
6.06
Human Site:
T262
Identified Species:
11.11
UniProt:
O75182
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75182
NP_056075.1
1162
133066
T262
Q
K
N
E
H
D
K
T
P
E
H
S
R
K
R
Chimpanzee
Pan troglodytes
XP_512485
1159
132821
T259
Q
K
N
E
H
D
K
T
P
E
H
S
R
K
R
Rhesus Macaque
Macaca mulatta
XP_001103619
1210
138821
Y296
A
L
T
E
Q
E
V
Y
A
Q
V
A
R
L
F
Dog
Lupus familis
XP_852728
1090
125608
R254
A
K
K
K
M
K
L
R
G
T
K
D
L
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q62141
1098
126387
H256
N
E
E
K
S
L
E
H
N
K
K
R
S
R
P
Rat
Rattus norvegicus
NP_001102231
1129
127784
A258
S
K
P
S
Q
L
Q
A
H
T
P
A
S
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511618
1116
128787
N256
Q
K
S
E
H
E
K
N
M
D
H
T
K
K
R
Chicken
Gallus gallus
XP_418257
1273
146269
N413
Q
K
T
E
H
E
K
N
L
E
H
S
K
K
R
Frog
Xenopus laevis
NP_001090601
1125
130319
L264
K
L
D
Y
Q
R
N
L
E
Q
S
R
K
R
S
Zebra Danio
Brachydanio rerio
NP_001038410
1196
136639
F268
F
S
K
V
A
S
L
F
K
G
Q
E
D
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
L401
F
E
N
Q
E
D
L
L
K
E
F
G
H
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48686
1353
153834
R278
K
K
Q
K
L
H
I
R
G
D
D
P
A
E
I
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
Q508
A
Q
A
Q
A
Q
A
Q
A
Q
V
E
Q
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.9
89.9
N.A.
87.6
50.9
N.A.
85.8
77.4
71.4
63.9
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
99.5
66.7
91.9
N.A.
91.3
64
N.A.
91
82.4
82.1
76
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
13.3
6.6
N.A.
0
6.6
N.A.
53.3
66.6
0
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
33.3
13.3
N.A.
33.3
33.3
N.A.
86.6
80
33.3
0
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
8
0
16
0
8
8
16
0
0
16
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
24
0
0
0
16
8
8
8
0
0
% D
% Glu:
0
16
8
39
8
24
8
0
8
31
0
16
0
8
0
% E
% Phe:
16
0
0
0
0
0
0
8
0
0
8
0
0
8
8
% F
% Gly:
0
0
0
0
0
0
0
0
16
8
0
8
0
0
0
% G
% His:
0
0
0
0
31
8
0
8
8
0
31
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
16
% I
% Lys:
16
54
16
24
0
8
31
0
16
8
16
0
24
31
8
% K
% Leu:
0
16
0
0
8
16
24
16
8
0
0
0
8
16
16
% L
% Met:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
24
0
0
0
8
16
8
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
16
0
8
8
0
0
8
% P
% Gln:
31
8
8
16
24
8
8
8
0
24
8
0
8
16
8
% Q
% Arg:
0
0
0
0
0
8
0
16
0
0
0
16
24
16
31
% R
% Ser:
8
8
8
8
8
8
0
0
0
0
8
24
16
8
8
% S
% Thr:
0
0
16
0
0
0
0
16
0
16
0
8
0
0
0
% T
% Val:
0
0
0
8
0
0
8
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _