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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3B
All Species:
7.27
Human Site:
T61
Identified Species:
13.33
UniProt:
O75182
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75182
NP_056075.1
1162
133066
T61
R
F
G
S
D
P
A
T
Y
N
G
F
L
E
I
Chimpanzee
Pan troglodytes
XP_512485
1159
132821
G61
S
D
P
A
T
Y
N
G
F
L
E
I
M
K
E
Rhesus Macaque
Macaca mulatta
XP_001103619
1210
138821
H74
M
P
Q
S
S
G
S
H
G
P
A
I
A
A
V
Dog
Lupus familis
XP_852728
1090
125608
D60
Q
L
F
H
E
H
P
D
L
I
V
G
F
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q62141
1098
126387
I61
T
Y
N
G
F
L
E
I
M
K
E
F
K
S
Q
Rat
Rattus norvegicus
NP_001102231
1129
127784
Y62
Q
Y
S
V
A
P
N
Y
Q
V
S
A
V
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511618
1116
128787
E61
A
T
Y
N
G
F
L
E
I
M
K
E
F
K
S
Chicken
Gallus gallus
XP_418257
1273
146269
T212
R
F
G
S
D
P
A
T
Y
N
G
F
L
E
I
Frog
Xenopus laevis
NP_001090601
1125
130319
S62
M
K
E
F
K
S
Q
S
I
D
T
P
G
V
I
Zebra Danio
Brachydanio rerio
NP_001038410
1196
136639
K61
N
D
P
G
I
Y
N
K
F
L
D
I
M
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
V171
Q
F
G
S
Q
P
Q
V
Y
N
D
F
L
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48686
1353
153834
T73
F
K
S
Q
R
V
D
T
A
G
V
I
T
R
V
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
I241
Q
F
S
S
R
P
D
I
Y
N
L
F
L
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.9
89.9
N.A.
87.6
50.9
N.A.
85.8
77.4
71.4
63.9
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
99.5
66.7
91.9
N.A.
91.3
64
N.A.
91
82.4
82.1
76
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
0
6.6
0
N.A.
6.6
6.6
N.A.
0
100
6.6
0
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
26.6
20
13.3
N.A.
13.3
26.6
N.A.
13.3
100
20
20
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
16
0
8
0
8
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
16
0
16
8
0
8
16
0
0
16
0
% D
% Glu:
0
0
8
0
8
0
8
8
0
0
16
8
0
16
16
% E
% Phe:
8
31
8
8
8
8
0
0
16
0
0
39
16
0
0
% F
% Gly:
0
0
24
16
8
8
0
8
8
8
16
8
8
0
0
% G
% His:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
16
16
8
0
31
0
0
39
% I
% Lys:
0
16
0
0
8
0
0
8
0
8
8
0
8
24
0
% K
% Leu:
0
8
0
0
0
8
8
0
8
16
8
0
31
0
0
% L
% Met:
16
0
0
0
0
0
0
0
8
8
0
0
16
0
0
% M
% Asn:
8
0
8
8
0
0
24
0
0
31
0
0
0
8
0
% N
% Pro:
0
8
16
0
0
39
8
0
0
8
0
8
0
8
0
% P
% Gln:
31
0
8
8
8
0
16
0
8
0
0
0
0
0
16
% Q
% Arg:
16
0
0
0
16
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
0
24
39
8
8
8
8
0
0
8
0
0
8
8
% S
% Thr:
8
8
0
0
8
0
0
24
0
0
8
0
8
0
0
% T
% Val:
0
0
0
8
0
8
0
8
0
8
16
0
8
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
8
0
0
16
0
8
31
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _