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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3B
All Species:
14.55
Human Site:
T866
Identified Species:
26.67
UniProt:
O75182
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75182
NP_056075.1
1162
133066
T866
L
E
G
S
I
D
P
T
Q
Y
E
D
T
L
R
Chimpanzee
Pan troglodytes
XP_512485
1159
132821
T863
L
E
G
S
I
D
P
T
Q
Y
E
D
T
L
R
Rhesus Macaque
Macaca mulatta
XP_001103619
1210
138821
S914
L
D
G
N
I
D
S
S
Q
Y
E
D
S
L
R
Dog
Lupus familis
XP_852728
1090
125608
S831
R
Q
L
H
H
L
V
S
D
D
V
C
L
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q62141
1098
126387
L834
V
Q
N
I
A
R
Q
L
H
H
L
V
S
D
D
Rat
Rattus norvegicus
NP_001102231
1129
127784
G857
G
A
P
K
K
H
N
G
V
G
G
S
P
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511618
1116
128787
A835
R
E
M
F
T
I
H
A
Y
I
G
F
T
M
D
Chicken
Gallus gallus
XP_418257
1273
146269
A992
R
E
M
F
T
I
H
A
Y
I
G
F
T
M
D
Frog
Xenopus laevis
NP_001090601
1125
130319
Y845
E
M
F
T
I
H
A
Y
I
V
F
T
I
D
K
Zebra Danio
Brachydanio rerio
NP_001038410
1196
136639
T903
L
D
G
N
L
E
S
T
Q
Y
E
D
T
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
K1013
Y
M
A
F
T
L
D
K
V
V
S
N
T
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48686
1353
153834
E919
K
V
E
R
E
E
G
E
L
S
P
N
G
D
F
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
Q1222
I
N
G
D
L
E
H
Q
W
F
E
E
S
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.9
89.9
N.A.
87.6
50.9
N.A.
85.8
77.4
71.4
63.9
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
99.5
66.7
91.9
N.A.
91.3
64
N.A.
91
82.4
82.1
76
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
66.6
0
N.A.
0
0
N.A.
13.3
13.3
6.6
66.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
13.3
N.A.
26.6
6.6
N.A.
20
20
20
93.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
0
8
16
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
16
0
8
0
24
8
0
8
8
0
31
0
24
24
% D
% Glu:
8
31
8
0
8
24
0
8
0
0
39
8
0
0
0
% E
% Phe:
0
0
8
24
0
0
0
0
0
8
8
16
0
0
8
% F
% Gly:
8
0
39
0
0
0
8
8
0
8
24
0
8
0
0
% G
% His:
0
0
0
8
8
16
24
0
8
8
0
0
0
0
0
% H
% Ile:
8
0
0
8
31
16
0
0
8
16
0
0
8
0
0
% I
% Lys:
8
0
0
8
8
0
0
8
0
0
0
0
0
8
16
% K
% Leu:
31
0
8
0
16
16
0
8
8
0
8
0
8
39
0
% L
% Met:
0
16
16
0
0
0
0
0
0
0
0
0
0
16
0
% M
% Asn:
0
8
8
16
0
0
8
0
0
0
0
16
0
0
0
% N
% Pro:
0
0
8
0
0
0
16
0
0
0
8
0
8
8
0
% P
% Gln:
0
16
0
0
0
0
8
8
31
0
0
0
0
0
0
% Q
% Arg:
24
0
0
8
0
8
0
0
0
0
0
0
0
0
47
% R
% Ser:
0
0
0
16
0
0
16
16
0
8
8
8
24
0
0
% S
% Thr:
0
0
0
8
24
0
0
24
0
0
0
8
47
0
0
% T
% Val:
8
8
0
0
0
0
8
0
16
16
8
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
16
31
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _