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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3B
All Species:
30.61
Human Site:
Y1074
Identified Species:
56.11
UniProt:
O75182
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75182
NP_056075.1
1162
133066
Y1074
F
I
V
N
S
E
D
Y
M
Y
R
R
G
T
L
Chimpanzee
Pan troglodytes
XP_512485
1159
132821
Y1071
F
I
V
N
S
E
D
Y
M
Y
R
R
G
T
L
Rhesus Macaque
Macaca mulatta
XP_001103619
1210
138821
Y1122
Y
V
I
K
S
E
D
Y
M
Y
R
R
T
A
L
Dog
Lupus familis
XP_852728
1090
125608
Q1016
L
C
R
A
K
Q
V
Q
P
L
V
L
L
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q62141
1098
126387
R1019
Y
R
R
G
T
L
C
R
A
K
Q
V
Q
P
L
Rat
Rattus norvegicus
NP_001102231
1129
127784
T1050
S
R
S
L
L
E
S
T
Y
Q
R
K
A
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511618
1116
128787
Y1028
F
I
M
N
S
E
D
Y
M
Y
R
R
G
T
L
Chicken
Gallus gallus
XP_418257
1273
146269
Y1185
F
I
M
N
S
E
D
Y
M
Y
R
R
G
A
L
Frog
Xenopus laevis
NP_001090601
1125
130319
Y1037
F
I
V
N
S
E
D
Y
M
Y
R
W
G
T
L
Zebra Danio
Brachydanio rerio
NP_001038410
1196
136639
Y1107
F
V
M
N
S
E
D
Y
M
Y
R
R
G
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
Y1198
Y
V
V
N
S
E
D
Y
M
Y
R
R
T
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48686
1353
153834
N1215
R
V
L
L
P
D
E
N
I
Y
R
I
E
C
R
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
G1429
A
N
D
N
T
Q
K
G
M
V
S
Q
K
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.9
89.9
N.A.
87.6
50.9
N.A.
85.8
77.4
71.4
63.9
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
99.5
66.7
91.9
N.A.
91.3
64
N.A.
91
82.4
82.1
76
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
60
0
N.A.
6.6
13.3
N.A.
93.3
86.6
93.3
80
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
80
6.6
N.A.
26.6
20
N.A.
100
93.3
93.3
93.3
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
8
0
0
0
8
24
0
% A
% Cys:
0
8
0
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
0
8
62
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
70
8
0
0
0
0
0
8
8
8
% E
% Phe:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
0
0
0
0
47
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
39
8
0
0
0
0
0
8
0
0
8
0
0
8
% I
% Lys:
0
0
0
8
8
0
8
0
0
8
0
8
8
8
0
% K
% Leu:
8
0
8
16
8
8
0
0
0
8
0
8
8
0
62
% L
% Met:
0
0
24
0
0
0
0
0
70
0
0
0
0
0
0
% M
% Asn:
0
8
0
62
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
8
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
16
0
8
0
8
8
8
8
0
8
% Q
% Arg:
8
16
16
0
0
0
0
8
0
0
77
54
0
8
8
% R
% Ser:
8
0
8
0
62
0
8
0
0
0
8
0
0
8
0
% S
% Thr:
0
0
0
0
16
0
0
8
0
0
0
0
16
31
0
% T
% Val:
0
31
31
0
0
0
8
0
0
8
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
24
0
0
0
0
0
0
62
8
70
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _