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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3B
All Species:
30.3
Human Site:
Y1155
Identified Species:
55.56
UniProt:
O75182
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75182
NP_056075.1
1162
133066
Y1155
V
T
R
Y
R
V
Q
Y
S
R
R
P
A
S
P
Chimpanzee
Pan troglodytes
XP_512485
1159
132821
Y1152
V
T
R
Y
R
V
Q
Y
S
R
R
P
A
S
P
Rhesus Macaque
Macaca mulatta
XP_001103619
1210
138821
Y1203
I
N
K
Y
R
V
K
Y
G
T
V
F
K
A
P
Dog
Lupus familis
XP_852728
1090
125608
Cat
Felis silvestris
Mouse
Mus musculus
Q62141
1098
126387
Y1091
V
T
R
Y
R
V
Q
Y
S
R
R
P
A
S
P
Rat
Rattus norvegicus
NP_001102231
1129
127784
L1120
S
P
E
L
R
E
H
L
A
Q
K
P
V
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511618
1116
128787
Y1109
V
N
R
Y
R
V
Q
Y
S
R
R
P
A
S
P
Chicken
Gallus gallus
XP_418257
1273
146269
Y1266
V
N
R
Y
R
V
Q
Y
S
R
R
P
A
S
P
Frog
Xenopus laevis
NP_001090601
1125
130319
Y1118
V
T
R
Y
R
V
Q
Y
P
R
R
P
A
S
P
Zebra Danio
Brachydanio rerio
NP_001038410
1196
136639
Y1188
V
N
R
Y
Q
V
H
Y
N
S
K
A
P
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
Y1278
H
R
K
F
K
V
A
Y
P
K
K
P
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48686
1353
153834
R1324
E
T
E
D
L
L
V
R
V
K
K
R
R
K
T
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
T1523
Q
D
D
N
I
E
T
T
G
N
T
E
S
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
51.9
89.9
N.A.
87.6
50.9
N.A.
85.8
77.4
71.4
63.9
N.A.
N.A.
N.A.
N.A.
44.5
Protein Similarity:
100
99.5
66.7
91.9
N.A.
91.3
64
N.A.
91
82.4
82.1
76
N.A.
N.A.
N.A.
N.A.
59
P-Site Identity:
100
100
33.3
0
N.A.
100
13.3
N.A.
93.3
93.3
93.3
33.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
60
0
N.A.
100
33.3
N.A.
93.3
93.3
93.3
60
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
0
0
8
47
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
8
0
16
0
0
16
0
0
0
0
0
8
8
8
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
16
0
8
0
8
0
0
16
31
0
8
8
0
% K
% Leu:
0
0
0
8
8
8
0
8
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
31
0
8
0
0
0
0
8
8
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
16
0
0
62
8
0
54
% P
% Gln:
8
0
0
0
8
0
47
0
0
8
0
0
0
0
0
% Q
% Arg:
0
8
54
0
62
0
0
8
0
47
47
8
8
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
39
8
0
0
8
54
8
% S
% Thr:
0
39
0
0
0
0
8
8
0
8
8
0
0
0
8
% T
% Val:
54
0
0
0
0
70
8
0
8
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
62
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _