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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP2C2
All Species:
19.39
Human Site:
S227
Identified Species:
35.56
UniProt:
O75185
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75185
NP_055676.2
946
103187
S227
T
G
E
A
E
P
C
S
K
T
D
S
P
L
T
Chimpanzee
Pan troglodytes
XP_511142
1080
117831
S361
T
G
E
A
E
P
C
S
K
T
D
S
P
L
T
Rhesus Macaque
Macaca mulatta
XP_001112571
947
103322
S228
T
G
E
A
E
P
C
S
K
T
D
S
P
L
T
Dog
Lupus familis
XP_536762
921
100381
S202
T
G
E
A
E
P
C
S
K
T
D
S
P
L
T
Cat
Felis silvestris
Mouse
Mus musculus
A7L9Z8
944
102509
G225
T
G
E
V
E
P
C
G
K
T
D
S
P
L
A
Rat
Rattus norvegicus
Q8R4C1
944
103002
S225
T
G
E
V
E
P
C
S
K
T
D
S
P
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509562
925
100997
V206
T
G
E
A
E
P
C
V
K
T
D
G
P
L
L
Chicken
Gallus gallus
Q9YGL9
1042
115411
N201
I
P
D
P
R
A
V
N
Q
D
K
K
N
M
L
Frog
Xenopus laevis
NP_001089971
916
100146
A205
I
H
G
S
I
D
E
A
S
G
I
A
T
L
S
Zebra Danio
Brachydanio rerio
XP_695172
925
101428
T205
E
T
T
P
C
T
K
T
S
A
P
Q
P
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22700
1020
111683
D203
D
P
R
A
V
N
Q
D
K
K
N
I
L
F
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SY55
998
109042
K202
N
A
V
Y
Q
D
K
K
N
I
L
F
S
G
T
Baker's Yeast
Sacchar. cerevisiae
P13586
950
104552
S219
T
S
Q
T
I
E
K
S
S
F
N
D
Q
P
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
93.6
86.3
N.A.
84.5
84.7
N.A.
85.7
32
73.3
62.4
N.A.
33.5
N.A.
N.A.
N.A.
Protein Similarity:
100
87.1
96
91.4
N.A.
91.8
92.8
N.A.
92.1
50.2
84
77.8
N.A.
52.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
86.6
N.A.
80
0
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
80
86.6
N.A.
80
26.6
33.3
13.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.8
47.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50
66.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
47
0
8
0
8
0
8
0
8
0
8
24
% A
% Cys:
0
0
0
0
8
0
54
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
16
0
8
0
8
54
8
0
0
0
% D
% Glu:
8
0
54
0
54
8
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% F
% Gly:
0
54
8
0
0
0
0
8
0
8
0
8
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
16
0
0
0
0
8
8
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
24
8
62
8
8
8
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
8
0
8
62
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
8
0
8
8
0
16
0
8
0
8
% N
% Pro:
0
16
0
16
0
54
0
0
0
0
8
0
62
8
0
% P
% Gln:
0
0
8
0
8
0
8
0
8
0
0
8
8
0
0
% Q
% Arg:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
8
0
0
0
47
24
0
0
47
8
0
16
% S
% Thr:
62
8
8
8
0
8
0
8
0
54
0
0
8
0
39
% T
% Val:
0
0
8
16
8
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _