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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP2C2 All Species: 28.79
Human Site: S486 Identified Species: 52.78
UniProt: O75185 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75185 NP_055676.2 946 103187 S486 R K K E I P F S S E Q K W M A
Chimpanzee Pan troglodytes XP_511142 1080 117831 S620 R K K E I P F S S E Q K W M A
Rhesus Macaque Macaca mulatta XP_001112571 947 103322 S487 R K K E I P F S S E Q K W M A
Dog Lupus familis XP_536762 921 100381 S461 R K K E I P F S S E Q K W M A
Cat Felis silvestris
Mouse Mus musculus A7L9Z8 944 102509 S484 R K K E I P F S S E Q K W M A
Rat Rattus norvegicus Q8R4C1 944 103002 S484 R K K E I P F S S E Q K W M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509562 925 100997 S465 R K K E I P F S S E Q K W M A
Chicken Gallus gallus Q9YGL9 1042 115411 R491 T L E F S R D R K S M S V Y C
Frog Xenopus laevis NP_001089971 916 100146 E457 K E I P F S S E Q R W M A V K
Zebra Danio Brachydanio rerio XP_695172 925 101428 S463 L E E I P F T S E Q K W M A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P22700 1020 111683 A470 D R R S A A I A C R G E I E T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SY55 998 109042 L464 M P S A L N M L S K H E R A S
Baker's Yeast Sacchar. cerevisiae P13586 950 104552 N478 K V Q E L P F N S K R K L M A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 93.6 86.3 N.A. 84.5 84.7 N.A. 85.7 32 73.3 62.4 N.A. 33.5 N.A. N.A. N.A.
Protein Similarity: 100 87.1 96 91.4 N.A. 91.8 92.8 N.A. 92.1 50.2 84 77.8 N.A. 52.3 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 0 0 6.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 6.6 20 33.3 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.8 47.7 N.A.
Protein Similarity: N.A. N.A. N.A. 50 66.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 8 0 8 0 0 0 0 8 16 62 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % C
% Asp: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 16 16 62 0 0 0 8 8 54 0 16 0 8 0 % E
% Phe: 0 0 0 8 8 8 62 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 8 8 54 0 8 0 0 0 0 0 8 0 0 % I
% Lys: 16 54 54 0 0 0 0 0 8 16 8 62 0 0 8 % K
% Leu: 8 8 0 0 16 0 0 8 0 0 0 0 8 0 0 % L
% Met: 8 0 0 0 0 0 8 0 0 0 8 8 8 62 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 8 8 62 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 8 8 54 0 0 0 0 % Q
% Arg: 54 8 8 0 0 8 0 8 0 16 8 0 8 0 0 % R
% Ser: 0 0 8 8 8 8 8 62 70 8 0 8 0 0 8 % S
% Thr: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % T
% Val: 0 8 0 0 0 0 0 0 0 0 0 0 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 8 54 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _