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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XYLB
All Species:
55.76
Human Site:
S194
Identified Species:
87.62
UniProt:
O75191
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75191
NP_005099.2
536
58382
S194
Y
S
H
T
E
R
I
S
L
V
S
S
F
A
A
Chimpanzee
Pan troglodytes
XP_526176
534
57843
S192
D
S
H
V
E
R
I
S
L
V
S
S
F
A
A
Rhesus Macaque
Macaca mulatta
XP_001086867
536
58445
S194
Y
S
H
T
E
R
I
S
L
V
S
S
F
A
A
Dog
Lupus familis
XP_851427
536
58088
S194
Y
S
H
T
E
R
I
S
L
V
S
S
F
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3TNA1
551
59525
S209
Y
S
H
S
E
R
I
S
L
V
S
S
F
A
A
Rat
Rattus norvegicus
Q3MIF4
536
57952
S194
Y
S
N
S
E
R
I
S
L
V
S
S
F
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418537
534
58330
S190
Y
A
Q
T
E
R
I
S
L
V
S
S
F
A
A
Frog
Xenopus laevis
NP_001108300
535
59040
S191
Y
S
Q
T
E
R
I
S
L
V
S
S
F
A
A
Zebra Danio
Brachydanio rerio
NP_956673
528
57893
S193
F
S
E
T
E
R
I
S
L
I
S
S
F
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650582
552
61136
S196
Y
E
E
A
N
R
I
S
L
V
S
S
F
I
S
Honey Bee
Apis mellifera
XP_393374
534
59125
S194
Y
N
S
T
K
R
I
S
L
I
S
S
F
L
A
Nematode Worm
Caenorhab. elegans
P30646
537
60302
S188
W
K
D
T
E
K
V
S
L
I
S
S
F
F
A
Sea Urchin
Strong. purpuratus
XP_794041
1489
163403
S1154
Y
Q
D
T
E
R
I
S
L
V
S
S
F
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001149021
562
61651
S197
Y
E
D
T
E
R
I
S
L
V
S
S
F
M
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42826
600
68302
S208
Y
E
K
T
K
T
I
S
L
V
S
N
F
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
95.5
91.9
N.A.
85.6
87.8
N.A.
N.A.
73.6
65.6
63.6
N.A.
43.4
53.1
37.4
23.5
Protein Similarity:
100
96.8
96.8
95.1
N.A.
90.3
93.8
N.A.
N.A.
84.3
80.2
78.9
N.A.
62.3
69.7
58.6
28.4
P-Site Identity:
100
86.6
100
100
N.A.
93.3
86.6
N.A.
N.A.
86.6
93.3
80
N.A.
60
66.6
53.3
80
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
66.6
86.6
80
80
Percent
Protein Identity:
N.A.
45.9
N.A.
N.A.
30
N.A.
Protein Similarity:
N.A.
62.1
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
80
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
80
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
0
0
0
0
0
0
60
87
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
20
14
0
80
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
100
7
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
94
0
0
20
0
0
0
7
0
% I
% Lys:
0
7
7
0
14
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
100
0
0
0
0
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
7
7
0
7
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
14
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
87
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
54
7
14
0
0
0
100
0
0
100
94
0
0
7
% S
% Thr:
0
0
0
74
0
7
0
0
0
0
0
0
0
0
7
% T
% Val:
0
0
0
7
0
0
7
0
0
80
0
0
0
7
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
80
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _