Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XYLB All Species: 55.15
Human Site: S214 Identified Species: 86.67
UniProt: O75191 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75191 NP_005099.2 536 58382 S214 S Y S P I D Y S D G S G M N L
Chimpanzee Pan troglodytes XP_526176 534 57843 S212 S Y S P I D Y S D G S G M N L
Rhesus Macaque Macaca mulatta XP_001086867 536 58445 S214 S Y S P I D Y S D G S G M N L
Dog Lupus familis XP_851427 536 58088 S214 S Y S P I D Y S D G S G M N L
Cat Felis silvestris
Mouse Mus musculus Q3TNA1 551 59525 S229 G Y S P I D Y S D G S G M N L
Rat Rattus norvegicus Q3MIF4 536 57952 S214 R Y S P I D Y S D G S G M N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418537 534 58330 S210 A Y A P I D Y S D G S G M N L
Frog Xenopus laevis NP_001108300 535 59040 S211 D Y A P I D Y S D G S G M N L
Zebra Danio Brachydanio rerio NP_956673 528 57893 S213 D F A P I D F S D G S G M N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650582 552 61136 S216 S V A P I D F S D G S G M N L
Honey Bee Apis mellifera XP_393374 534 59125 S214 D F A P I D W S D G S G M N L
Nematode Worm Caenorhab. elegans P30646 537 60302 T208 K Y A L I E L T D G S G M N L
Sea Urchin Strong. purpuratus XP_794041 1489 163403 S1174 D Y A A I D H S D G S G M N L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001149021 562 61651 T217 S Y A S I D E T D G A G M N L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P42826 600 68302 A228 H L V E L E E A D A C G M N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.5 95.5 91.9 N.A. 85.6 87.8 N.A. N.A. 73.6 65.6 63.6 N.A. 43.4 53.1 37.4 23.5
Protein Similarity: 100 96.8 96.8 95.1 N.A. 90.3 93.8 N.A. N.A. 84.3 80.2 78.9 N.A. 62.3 69.7 58.6 28.4
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 86.6 86.6 73.3 N.A. 80 73.3 60 73.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 100 93.3 93.3 N.A. 93.3 93.3 80 86.6
Percent
Protein Identity: N.A. 45.9 N.A. N.A. 30 N.A.
Protein Similarity: N.A. 62.1 N.A. N.A. 50.1 N.A.
P-Site Identity: N.A. 66.6 N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. 86.6 N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 54 7 0 0 0 7 0 7 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 27 0 0 0 0 87 0 0 100 0 0 0 0 0 0 % D
% Glu: 0 0 0 7 0 14 14 0 0 0 0 0 0 0 0 % E
% Phe: 0 14 0 0 0 0 14 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 0 0 0 0 94 0 100 0 0 0 % G
% His: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 94 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 7 0 7 7 0 7 0 0 0 0 0 0 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % N
% Pro: 0 0 0 74 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 40 0 40 7 0 0 0 80 0 0 87 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % T
% Val: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 74 0 0 0 0 54 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _