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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XYLB All Species: 16.12
Human Site: T531 Identified Species: 25.33
UniProt: O75191 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75191 NP_005099.2 536 58382 T531 E Q R I L S Q T R G P P E _ _
Chimpanzee Pan troglodytes XP_526176 534 57843 T529 E Q K I L S Q T R G P P E _ _
Rhesus Macaque Macaca mulatta XP_001086867 536 58445 T531 E Q R I L S Q T R G P L E _ _
Dog Lupus familis XP_851427 536 58088 T531 E Q R I L A Q T R G P P E _ _
Cat Felis silvestris
Mouse Mus musculus Q3TNA1 551 59525 A546 E Q R I L S T A Q R P L E _ _
Rat Rattus norvegicus Q3MIF4 536 57952 A531 E Q R I L S K A R G P L E _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418537 534 58330 P527 E Q K V I Y N P T S S C L A K
Frog Xenopus laevis NP_001108300 535 59040 S529 E N A V V R G S Q S R C R N _
Zebra Danio Brachydanio rerio NP_956673 528 57893 F519 Y L P M L E R F A K L E E Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650582 552 61136 E542 P M L Q R Y R E M A R V L S N
Honey Bee Apis mellifera XP_393374 534 59125 R521 K A M V V R Y R K I I E Q I K
Nematode Worm Caenorhab. elegans P30646 537 60302 K525 E V Y S N L F K T F K S R F D
Sea Urchin Strong. purpuratus XP_794041 1489 163403
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001149021 562 61651 R546 Q K Y T L L M R K R M E I E R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P42826 600 68302 S573 F P W H V M E S I S D V D N E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.5 95.5 91.9 N.A. 85.6 87.8 N.A. N.A. 73.6 65.6 63.6 N.A. 43.4 53.1 37.4 23.5
Protein Similarity: 100 96.8 96.8 95.1 N.A. 90.3 93.8 N.A. N.A. 84.3 80.2 78.9 N.A. 62.3 69.7 58.6 28.4
P-Site Identity: 100 92.3 92.3 92.3 N.A. 61.5 76.9 N.A. N.A. 13.3 7.1 13.3 N.A. 0 0 6.6 0
P-Site Similarity: 100 100 92.3 100 N.A. 69.2 84.6 N.A. N.A. 33.3 35.7 26.6 N.A. 6.6 40 6.6 0
Percent
Protein Identity: N.A. 45.9 N.A. N.A. 30 N.A.
Protein Similarity: N.A. 62.1 N.A. N.A. 50.1 N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. 0 N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 0 7 0 14 7 7 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 7 % D
% Glu: 60 0 0 0 0 7 7 7 0 0 0 20 47 7 7 % E
% Phe: 7 0 0 0 0 0 7 7 0 7 0 0 0 7 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 34 0 0 0 0 0 % G
% His: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 40 7 0 0 0 7 7 7 0 7 7 0 % I
% Lys: 7 7 14 0 0 0 7 7 14 7 7 0 0 0 14 % K
% Leu: 0 7 7 0 54 14 0 0 0 0 7 20 14 0 7 % L
% Met: 0 7 7 7 0 7 7 0 7 0 7 0 0 0 0 % M
% Asn: 0 7 0 0 7 0 7 0 0 0 0 0 0 14 7 % N
% Pro: 7 7 7 0 0 0 0 7 0 0 40 20 0 0 0 % P
% Gln: 7 47 0 7 0 0 27 0 14 0 0 0 7 7 0 % Q
% Arg: 0 0 34 0 7 14 14 14 34 14 14 0 14 0 7 % R
% Ser: 0 0 0 7 0 34 0 14 0 20 7 7 0 7 0 % S
% Thr: 0 0 0 7 0 0 7 27 14 0 0 0 0 0 0 % T
% Val: 0 7 0 20 20 0 0 0 0 0 0 14 0 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 14 0 0 14 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 40 47 % _