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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XYLB
All Species:
46.36
Human Site:
Y168
Identified Species:
72.86
UniProt:
O75191
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75191
NP_005099.2
536
58382
Y168
C
L
T
G
S
R
A
Y
E
R
F
T
G
N
Q
Chimpanzee
Pan troglodytes
XP_526176
534
57843
R166
L
S
C
L
T
G
S
R
A
Y
E
R
T
G
G
Rhesus Macaque
Macaca mulatta
XP_001086867
536
58445
Y168
C
L
T
G
S
R
A
Y
E
R
F
T
G
N
Q
Dog
Lupus familis
XP_851427
536
58088
Y168
S
L
T
G
S
R
A
Y
E
R
F
T
G
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3TNA1
551
59525
Y183
C
L
T
G
S
R
A
Y
E
R
F
T
G
N
Q
Rat
Rattus norvegicus
Q3MIF4
536
57952
Y168
C
L
T
G
S
R
A
Y
E
R
F
T
G
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418537
534
58330
Y164
N
I
T
G
S
R
A
Y
E
R
F
T
G
N
Q
Frog
Xenopus laevis
NP_001108300
535
59040
Y165
N
I
T
G
S
R
A
Y
E
R
F
T
G
N
Q
Zebra Danio
Brachydanio rerio
NP_956673
528
57893
Y167
D
I
T
G
S
R
A
Y
E
R
F
T
G
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650582
552
61136
Y170
E
L
T
G
S
K
C
Y
E
R
F
T
G
P
Q
Honey Bee
Apis mellifera
XP_393374
534
59125
Y168
E
I
T
G
S
R
A
Y
E
R
F
S
G
P
Q
Nematode Worm
Caenorhab. elegans
P30646
537
60302
H162
K
L
T
G
S
R
A
H
H
R
F
S
A
A
Q
Sea Urchin
Strong. purpuratus
XP_794041
1489
163403
Y1128
N
I
T
G
S
R
A
Y
E
R
F
T
G
N
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001149021
562
61651
Y171
K
L
T
G
S
R
A
Y
E
R
F
T
G
P
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42826
600
68302
H182
Q
L
T
G
S
R
A
H
F
R
F
T
G
P
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
95.5
91.9
N.A.
85.6
87.8
N.A.
N.A.
73.6
65.6
63.6
N.A.
43.4
53.1
37.4
23.5
Protein Similarity:
100
96.8
96.8
95.1
N.A.
90.3
93.8
N.A.
N.A.
84.3
80.2
78.9
N.A.
62.3
69.7
58.6
28.4
P-Site Identity:
100
0
100
93.3
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
73.3
73.3
60
86.6
P-Site Similarity:
100
13.3
100
93.3
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
80
86.6
73.3
93.3
Percent
Protein Identity:
N.A.
45.9
N.A.
N.A.
30
N.A.
Protein Similarity:
N.A.
62.1
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
86.6
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
87
0
7
0
0
0
7
7
0
% A
% Cys:
27
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
14
0
0
0
0
0
0
0
80
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
94
0
0
0
0
% F
% Gly:
0
0
0
94
0
7
0
0
0
0
0
0
87
7
7
% G
% His:
0
0
0
0
0
0
0
14
7
0
0
0
0
0
0
% H
% Ile:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
14
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
60
0
7
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
27
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
94
% Q
% Arg:
0
0
0
0
0
87
0
7
0
94
0
7
0
0
0
% R
% Ser:
7
7
0
0
94
0
7
0
0
0
0
14
0
0
0
% S
% Thr:
0
0
94
0
7
0
0
0
0
0
0
80
7
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _