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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XYLB All Species: 29.7
Human Site: Y513 Identified Species: 46.67
UniProt: O75191 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75191 NP_005099.2 536 58382 Y513 S P G A S Q V Y E A L L P Q Y
Chimpanzee Pan troglodytes XP_526176 534 57843 Y511 S P G A S Q V Y K A L L P Q Y
Rhesus Macaque Macaca mulatta XP_001086867 536 58445 Y513 S L G A S Q V Y E A L L P Q Y
Dog Lupus familis XP_851427 536 58088 Y513 S S G A S Q V Y E A L L P Q Y
Cat Felis silvestris
Mouse Mus musculus Q3TNA1 551 59525 Y528 N P G A S Q V Y A A L L P R Y
Rat Rattus norvegicus Q3MIF4 536 57952 Y513 N P G A S Q V Y A A L L P R Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418537 534 58330 Y509 T A G A E E L Y H P L L K R Y
Frog Xenopus laevis NP_001108300 535 59040 Y511 R P G A D K I Y G A L L K R Y
Zebra Danio Brachydanio rerio NP_956673 528 57893 A501 N A P E P Q L A V R P T P G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650582 552 61136 E524 N K L S L V C E P H K D S E E
Honey Bee Apis mellifera XP_393374 534 59125 C503 L P E P T L I C R P Y D D A E
Nematode Worm Caenorhab. elegans P30646 537 60302 S507 Y Y P C D N V S L A C Q P I S
Sea Urchin Strong. purpuratus XP_794041 1489 163403 T1467 K Q A A T P N T H A A Q V Y N
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001149021 562 61651 A528 G S K L A V P A G D K E Q D R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P42826 600 68302 A555 L Y D S N K I A V P F D K F L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.5 95.5 91.9 N.A. 85.6 87.8 N.A. N.A. 73.6 65.6 63.6 N.A. 43.4 53.1 37.4 23.5
Protein Similarity: 100 96.8 96.8 95.1 N.A. 90.3 93.8 N.A. N.A. 84.3 80.2 78.9 N.A. 62.3 69.7 58.6 28.4
P-Site Identity: 100 93.3 93.3 93.3 N.A. 80 80 N.A. N.A. 40 53.3 13.3 N.A. 0 6.6 20 13.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. N.A. 66.6 73.3 26.6 N.A. 20 20 20 20
Percent
Protein Identity: N.A. 45.9 N.A. N.A. 30 N.A.
Protein Similarity: N.A. 62.1 N.A. N.A. 50.1 N.A.
P-Site Identity: N.A. 0 N.A. N.A. 0 N.A.
P-Site Similarity: N.A. 6.6 N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 7 60 7 0 0 20 14 60 7 0 0 7 7 % A
% Cys: 0 0 0 7 0 0 7 7 0 0 7 0 0 0 0 % C
% Asp: 0 0 7 0 14 0 0 0 0 7 0 20 7 7 0 % D
% Glu: 0 0 7 7 7 7 0 7 20 0 0 7 0 7 14 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % F
% Gly: 7 0 54 0 0 0 0 0 14 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 14 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 20 0 0 0 0 0 0 7 0 % I
% Lys: 7 7 7 0 0 14 0 0 7 0 14 0 20 0 0 % K
% Leu: 14 7 7 7 7 7 14 0 7 0 54 54 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 27 0 0 0 7 7 7 0 0 0 0 0 0 0 7 % N
% Pro: 0 40 14 7 7 7 7 0 7 20 7 0 54 0 0 % P
% Gln: 0 7 0 0 0 47 0 0 0 0 0 14 7 27 0 % Q
% Arg: 7 0 0 0 0 0 0 0 7 7 0 0 0 27 7 % R
% Ser: 27 14 0 14 40 0 0 7 0 0 0 0 7 0 7 % S
% Thr: 7 0 0 0 14 0 0 7 0 0 0 7 0 0 0 % T
% Val: 0 0 0 0 0 14 47 0 14 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 14 0 0 0 0 0 54 0 0 7 0 0 7 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _