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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP5
All Species:
23.94
Human Site:
Y1517
Identified Species:
47.88
UniProt:
O75197
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75197
NP_002326.2
1615
179145
Y1517
L
Y
N
M
D
M
F
Y
S
S
N
I
P
A
T
Chimpanzee
Pan troglodytes
XP_508605
1701
188045
Y1603
L
Y
N
M
D
M
F
Y
S
S
N
I
P
A
T
Rhesus Macaque
Macaca mulatta
XP_001117791
1209
134638
L1112
S
P
D
L
I
L
P
L
H
G
L
R
N
V
K
Dog
Lupus familis
XP_866872
1612
180302
Y1505
H
Y
T
M
E
F
G
Y
S
S
N
S
P
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91VN0
1614
178879
Y1516
L
Y
N
V
D
V
F
Y
S
S
G
I
P
A
T
Rat
Rattus norvegicus
Q9QYP1
1905
211861
G1729
L
H
V
S
Y
A
V
G
G
L
L
S
V
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508455
1480
165692
Y1371
H
Y
T
M
E
F
G
Y
S
S
N
S
P
S
T
Chicken
Gallus gallus
NP_001012915
1616
180864
Y1518
L
Y
N
A
E
M
F
Y
S
S
N
I
P
S
T
Frog
Xenopus laevis
NP_001079163
1605
179641
Y1507
L
Y
N
T
E
V
F
Y
S
S
N
S
P
S
T
Zebra Danio
Brachydanio rerio
XP_696943
1405
157848
N1308
A
E
V
F
Y
S
S
N
S
P
S
T
T
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P98163
1984
219502
T1649
F
V
D
Q
H
M
R
T
L
E
R
I
S
Y
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202408
1322
148003
I1225
P
T
P
C
S
T
D
I
C
E
D
S
E
P
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
61.5
70
N.A.
93.9
28.4
N.A.
63.9
87.8
80.1
66.5
N.A.
20.3
N.A.
N.A.
41.6
Protein Similarity:
100
94.4
62.9
83.2
N.A.
96.4
43.3
N.A.
76.1
94
88.7
75.6
N.A.
34.8
N.A.
N.A.
54.9
P-Site Identity:
100
100
0
53.3
N.A.
80
6.6
N.A.
53.3
80
66.6
6.6
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
20
66.6
N.A.
93.3
13.3
N.A.
66.6
93.3
86.6
20
N.A.
20
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
9
0
0
0
0
0
0
0
25
0
% A
% Cys:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
17
0
25
0
9
0
0
0
9
0
0
0
0
% D
% Glu:
0
9
0
0
34
0
0
0
0
17
0
0
9
0
0
% E
% Phe:
9
0
0
9
0
17
42
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
17
9
9
9
9
0
0
0
0
% G
% His:
17
9
0
0
9
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
9
0
0
0
42
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
50
0
0
9
0
9
0
9
9
9
17
0
0
9
9
% L
% Met:
0
0
0
34
0
34
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
42
0
0
0
0
9
0
0
50
0
9
0
0
% N
% Pro:
9
9
9
0
0
0
9
0
0
9
0
0
59
9
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
9
9
0
9
9
% R
% Ser:
9
0
0
9
9
9
9
0
67
59
9
42
9
34
9
% S
% Thr:
0
9
17
9
0
9
0
9
0
0
0
9
9
0
59
% T
% Val:
0
9
17
9
0
17
9
0
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
59
0
0
17
0
0
59
0
0
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _