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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GADD45B
All Species:
16.36
Human Site:
T108
Identified Species:
40
UniProt:
O75293
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75293
NP_056490.2
160
17818
T108
L
L
G
E
P
A
E
T
Q
G
T
T
E
A
R
Chimpanzee
Pan troglodytes
XP_001151800
145
16182
Q94
L
G
E
P
A
E
T
Q
G
T
T
E
A
R
D
Rhesus Macaque
Macaca mulatta
XP_001098598
160
17832
T108
L
L
G
E
P
A
E
T
Q
G
T
T
E
A
R
Dog
Lupus familis
XP_542187
160
17756
T108
L
L
G
E
P
A
E
T
Q
G
T
A
E
A
R
Cat
Felis silvestris
Mouse
Mus musculus
P22339
160
17765
T108
L
L
G
E
P
A
E
T
L
G
T
T
E
A
R
Rat
Rattus norvegicus
P48317
165
18461
S113
N
D
K
S
P
A
E
S
G
G
L
A
Q
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510262
158
17634
E106
A
E
L
L
G
E
P
E
D
E
D
S
E
P
R
Chicken
Gallus gallus
NP_001038131
159
17392
G108
L
A
A
A
L
G
S
G
E
E
S
G
E
P
R
Frog
Xenopus laevis
NP_001079598
159
17753
T108
V
A
Q
I
L
G
F
T
D
E
S
A
E
P
K
Zebra Danio
Brachydanio rerio
NP_998196
159
17866
V108
V
L
D
E
P
A
T
V
E
N
S
E
P
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.6
99.3
98.1
N.A.
93.1
56.3
N.A.
83.1
60
58.7
68.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.6
100
99.3
N.A.
96.2
73.9
N.A.
92.5
72.5
76.2
80.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
26.6
N.A.
13.3
20
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
93.3
N.A.
93.3
40
N.A.
20
33.3
33.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
10
10
10
60
0
0
0
0
0
30
10
40
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
20
0
10
0
0
0
20
% D
% Glu:
0
10
10
50
0
20
50
10
20
30
0
20
70
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
40
0
10
20
0
10
20
50
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
60
50
10
10
20
0
0
0
10
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
60
0
10
0
0
0
0
0
10
30
10
% P
% Gln:
0
0
10
0
0
0
0
10
30
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
60
% R
% Ser:
0
0
0
10
0
0
10
10
0
0
30
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
20
50
0
10
50
30
0
10
0
% T
% Val:
20
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _