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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GADD45B All Species: 33.94
Human Site: Y41 Identified Species: 82.96
UniProt: O75293 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75293 NP_056490.2 160 17818 Y41 D R L T V G V Y E S A K L M N
Chimpanzee Pan troglodytes XP_001151800 145 16182 D35 S A K L M N V D P D S V V L C
Rhesus Macaque Macaca mulatta XP_001098598 160 17832 Y41 D R L T V G V Y E S A K L M N
Dog Lupus familis XP_542187 160 17756 Y41 D R L T V G V Y E S A K L M N
Cat Felis silvestris
Mouse Mus musculus P22339 160 17765 Y41 D R L T V G V Y E A A K L M N
Rat Rattus norvegicus P48317 165 18461 Y41 R T I T V G V Y E A A K L L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510262 158 17634 Y41 D C L T V G V Y E S A K L M N
Chicken Gallus gallus NP_001038131 159 17392 Y44 G C L T A G V Y E S A K L M N
Frog Xenopus laevis NP_001079598 159 17753 Y44 E C L T V G V Y E S A K V M N
Zebra Danio Brachydanio rerio NP_998196 159 17866 Y41 D C L T V G V Y E S A K L M N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.6 99.3 98.1 N.A. 93.1 56.3 N.A. 83.1 60 58.7 68.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 90.6 100 99.3 N.A. 96.2 73.9 N.A. 92.5 72.5 76.2 80.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 93.3 66.6 N.A. 93.3 80 80 93.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 100 86.6 N.A. 93.3 80 93.3 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 0 0 0 20 90 0 0 0 0 % A
% Cys: 0 40 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 60 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 90 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 90 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 90 0 0 0 % K
% Leu: 0 0 80 10 0 0 0 0 0 0 0 0 80 20 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 80 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 90 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 0 0 70 10 0 0 0 0 % S
% Thr: 0 10 0 90 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 80 0 100 0 0 0 0 10 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _