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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF259
All Species:
18.18
Human Site:
S388
Identified Species:
36.36
UniProt:
O75312
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75312
NP_003895.1
459
50925
S388
T
E
R
L
Q
E
F
S
Q
K
M
D
Q
I
I
Chimpanzee
Pan troglodytes
XP_001152978
459
50861
S388
T
E
G
L
Q
E
F
S
Q
K
M
D
Q
I
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850312
460
51120
S389
M
E
K
L
Q
E
F
S
Q
K
L
D
Q
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q62384
459
50696
S388
S
E
K
L
Q
E
F
S
Q
K
L
G
Q
I
I
Rat
Rattus norvegicus
NP_001131118
459
50836
S388
S
E
K
L
Q
E
F
S
Q
K
L
G
Q
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026668
231
25792
K170
L
Q
E
V
I
E
G
K
T
K
T
V
F
I
M
Frog
Xenopus laevis
NP_001121222
446
49990
G379
R
E
K
L
E
E
F
G
R
T
I
D
Q
I
L
Zebra Danio
Brachydanio rerio
NP_998273
441
49235
G375
V
E
K
L
Q
L
F
G
Q
K
I
D
K
I
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572532
457
51282
T390
Q
M
Q
R
F
L
D
T
F
E
D
V
M
N
L
Honey Bee
Apis mellifera
XP_394704
445
50434
I382
V
K
R
M
E
I
F
I
S
H
L
N
E
V
L
Nematode Worm
Caenorhab. elegans
O16999
455
50911
L377
K
S
A
V
T
T
F
L
E
K
L
D
D
I
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53303
486
55054
F424
T
K
A
R
W
V
E
F
F
A
K
L
K
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
89.7
N.A.
90.4
89.1
N.A.
N.A.
40.5
68.6
68.6
N.A.
48.5
51.4
41.1
N.A.
Protein Similarity:
100
99.7
N.A.
94.3
N.A.
94.3
92.8
N.A.
N.A.
45
82.5
81.2
N.A.
67.3
69.2
61.4
N.A.
P-Site Identity:
100
93.3
N.A.
73.3
N.A.
73.3
73.3
N.A.
N.A.
20
46.6
53.3
N.A.
0
13.3
33.3
N.A.
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
40
80
80
N.A.
26.6
66.6
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
0
0
9
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
9
50
9
0
0
% D
% Glu:
0
59
9
0
17
59
9
0
9
9
0
0
9
9
0
% E
% Phe:
0
0
0
0
9
0
75
9
17
0
0
0
9
0
0
% F
% Gly:
0
0
9
0
0
0
9
17
0
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
0
9
0
0
17
0
0
75
42
% I
% Lys:
9
17
42
0
0
0
0
9
0
67
9
0
17
0
0
% K
% Leu:
9
0
0
59
0
17
0
9
0
0
42
9
0
0
34
% L
% Met:
9
9
0
9
0
0
0
0
0
0
17
0
9
0
17
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
9
9
0
50
0
0
0
50
0
0
0
50
0
0
% Q
% Arg:
9
0
17
17
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
17
9
0
0
0
0
0
42
9
0
0
0
0
0
0
% S
% Thr:
25
0
0
0
9
9
0
9
9
9
9
0
0
0
0
% T
% Val:
17
0
0
17
0
9
0
0
0
0
0
17
0
9
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _