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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP12
All Species:
22.42
Human Site:
T166
Identified Species:
41.11
UniProt:
O75317
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75317
NP_872294.1
370
42858
T166
D
N
E
N
N
N
S
T
P
D
P
T
W
V
H
Chimpanzee
Pan troglodytes
XP_001135418
673
75605
T469
D
N
E
N
N
N
S
T
P
D
P
T
W
V
H
Rhesus Macaque
Macaca mulatta
XP_001117796
475
54263
T271
D
N
E
N
N
N
S
T
P
D
P
T
W
V
H
Dog
Lupus familis
XP_543159
370
42853
T166
D
S
E
N
N
N
S
T
P
D
P
T
W
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9M2
370
42895
T166
D
N
E
D
N
N
S
T
P
D
P
T
W
V
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519444
446
51141
P242
D
S
E
N
N
N
S
P
P
D
P
T
W
V
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Q52KZ6
370
42846
A166
D
N
E
N
N
N
S
A
P
D
P
T
W
V
H
Zebra Danio
Brachydanio rerio
A4FUN7
371
43008
P167
S
Q
N
N
N
S
T
P
P
S
T
T
W
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625039
354
40655
F158
P
T
W
V
H
E
I
F
Q
G
I
L
T
S
E
Nematode Worm
Caenorhab. elegans
P34547
426
48259
S191
G
N
E
F
L
N
K
S
D
T
T
T
W
I
H
Sea Urchin
Strong. purpuratus
XP_783431
365
41716
K160
N
G
N
N
N
D
M
K
T
E
P
T
W
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24454
371
42429
E166
A
N
G
V
V
H
K
E
P
I
V
T
W
V
H
Baker's Yeast
Sacchar. cerevisiae
P38187
747
83846
S468
I
N
S
D
S
E
P
S
K
S
K
N
F
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.9
76
99.1
N.A.
98.3
N.A.
N.A.
79.1
N.A.
98.3
93.2
N.A.
N.A.
72.1
59.1
76.7
Protein Similarity:
100
54.9
77.4
100
N.A.
99.7
N.A.
N.A.
81.6
N.A.
99.4
97.5
N.A.
N.A.
81.3
70.6
86.7
P-Site Identity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
86.6
N.A.
93.3
46.6
N.A.
N.A.
0
40
40
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
93.3
N.A.
93.3
60
N.A.
N.A.
6.6
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
57.4
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
73.3
34
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
0
16
0
8
0
0
8
54
0
0
0
0
0
% D
% Glu:
0
0
62
0
0
16
0
8
0
8
0
0
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
8
8
8
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
85
% H
% Ile:
8
0
0
0
0
0
8
0
0
8
8
0
0
24
0
% I
% Lys:
0
0
0
0
0
0
16
8
8
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
62
16
62
70
62
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
0
0
0
0
0
8
16
70
0
62
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
16
8
0
8
8
54
16
0
16
0
0
0
8
8
% S
% Thr:
0
8
0
0
0
0
8
39
8
8
16
85
8
0
0
% T
% Val:
0
0
0
16
8
0
0
0
0
0
8
0
0
70
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
85
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _