KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP12
All Species:
43.03
Human Site:
T222
Identified Species:
78.89
UniProt:
O75317
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75317
NP_872294.1
370
42858
T222
C
L
R
G
F
S
N
T
E
T
L
C
S
E
Y
Chimpanzee
Pan troglodytes
XP_001135418
673
75605
T525
C
L
R
G
F
S
N
T
E
T
L
C
S
E
Y
Rhesus Macaque
Macaca mulatta
XP_001117796
475
54263
T327
C
L
R
G
F
S
N
T
E
T
L
C
S
E
Y
Dog
Lupus familis
XP_543159
370
42853
T222
C
L
R
G
F
S
N
T
E
T
L
C
S
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9M2
370
42895
T222
C
L
R
G
F
S
N
T
E
T
L
C
S
E
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519444
446
51141
T298
C
L
R
G
F
S
N
T
E
T
L
C
S
E
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Q52KZ6
370
42846
T222
C
L
R
G
F
S
N
T
E
T
L
C
S
E
Y
Zebra Danio
Brachydanio rerio
A4FUN7
371
43008
T223
C
L
R
G
F
S
N
T
E
T
L
C
S
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625039
354
40655
K214
L
C
S
D
N
K
F
K
C
D
H
C
S
S
Y
Nematode Worm
Caenorhab. elegans
P34547
426
48259
T247
C
L
R
V
F
S
E
T
E
T
L
C
G
D
Q
Sea Urchin
Strong. purpuratus
XP_783431
365
41716
T216
C
L
R
G
F
S
N
T
E
T
L
C
H
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O24454
371
42429
T222
C
L
K
N
F
S
S
T
E
T
L
H
A
E
D
Baker's Yeast
Sacchar. cerevisiae
P38187
747
83846
H524
Q
E
I
L
K
S
Y
H
Q
R
E
M
L
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
54.9
76
99.1
N.A.
98.3
N.A.
N.A.
79.1
N.A.
98.3
93.2
N.A.
N.A.
72.1
59.1
76.7
Protein Similarity:
100
54.9
77.4
100
N.A.
99.7
N.A.
N.A.
81.6
N.A.
99.4
97.5
N.A.
N.A.
81.3
70.6
86.7
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
20
66.6
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
20
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
57.4
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
73.3
34
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
85
8
0
0
0
0
0
0
8
0
0
85
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
8
% D
% Glu:
0
8
0
0
0
0
8
0
85
0
8
0
0
77
0
% E
% Phe:
0
0
0
0
85
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
70
0
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
8
8
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
8
8
0
8
0
0
0
0
0
0
0
% K
% Leu:
8
85
0
8
0
0
0
0
0
0
85
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
8
0
70
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
77
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
93
8
0
0
0
0
0
70
8
0
% S
% Thr:
0
0
0
0
0
0
0
85
0
85
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
77
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _