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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMMR
All Species:
14.55
Human Site:
S447
Identified Species:
24.62
UniProt:
O75330
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75330
NP_036616.2
724
84100
S447
L
L
Q
E
K
Y
D
S
M
V
Q
S
L
E
D
Chimpanzee
Pan troglodytes
XP_001145921
725
84298
T448
L
L
Q
E
K
Y
D
T
M
V
Q
S
L
E
D
Rhesus Macaque
Macaca mulatta
XP_001088518
714
82407
S448
L
L
Q
E
K
Y
N
S
T
V
Q
S
L
E
D
Dog
Lupus familis
XP_854651
712
82189
S448
L
L
Q
E
S
Y
H
S
I
V
Q
S
L
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q00547
794
91781
D468
S
V
Q
E
K
Y
N
D
T
A
Q
S
L
R
D
Rat
Rattus norvegicus
P97779
498
57840
R275
K
V
A
M
A
E
K
R
V
E
D
V
Q
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510078
1224
143817
K765
E
I
Q
N
L
K
D
K
L
K
L
R
E
Q
E
Chicken
Gallus gallus
XP_414495
735
84777
N458
Q
I
Q
E
E
L
N
N
T
L
H
K
L
G
E
Frog
Xenopus laevis
Q91785
1388
159123
A988
D
L
E
K
K
N
T
A
D
K
E
V
V
A
D
Zebra Danio
Brachydanio rerio
NP_955874
903
104691
A463
K
L
K
E
E
H
C
A
V
T
K
Q
L
E
E
Tiger Blowfish
Takifugu rubipres
NP_001011731
834
97660
K527
Q
L
Q
D
E
M
E
K
A
Q
K
L
M
E
E
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
Q865
K
L
H
D
E
I
S
Q
L
K
S
Q
A
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785252
773
89752
T502
K
A
K
E
S
L
M
T
Q
V
E
L
L
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32380
944
111763
K551
H
M
K
E
N
Y
E
K
Q
L
E
S
L
R
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
94.8
85
N.A.
68.8
50.2
N.A.
36.3
49.7
21.2
33.5
26.5
22.5
N.A.
N.A.
24.3
Protein Similarity:
100
98.7
96.4
91.5
N.A.
78
57.5
N.A.
47.2
68.5
35.7
50.9
48.8
32.3
N.A.
N.A.
46.9
P-Site Identity:
100
93.3
86.6
73.3
N.A.
53.3
0
N.A.
13.3
20
20
26.6
20
13.3
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
80
N.A.
66.6
20
N.A.
40
60
53.3
73.3
60
40
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
0
0
15
8
8
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
15
0
0
22
8
8
0
8
0
0
0
43
% D
% Glu:
8
0
8
65
29
8
15
0
0
8
22
0
8
43
36
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% G
% His:
8
0
8
0
0
8
8
0
0
0
8
0
0
0
0
% H
% Ile:
0
15
0
0
0
8
0
0
8
0
0
0
0
0
0
% I
% Lys:
29
0
22
8
36
8
8
22
0
22
15
8
0
0
8
% K
% Leu:
29
58
0
0
8
15
0
0
15
15
8
15
65
0
0
% L
% Met:
0
8
0
8
0
8
8
0
15
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
8
8
22
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
0
58
0
0
0
0
8
15
8
36
15
8
22
8
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
8
0
15
0
% R
% Ser:
8
0
0
0
15
0
8
22
0
0
8
43
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
15
22
8
0
0
0
0
0
% T
% Val:
0
15
0
0
0
0
0
0
15
36
0
15
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
43
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _