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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMMR
All Species:
8.48
Human Site:
S653
Identified Species:
14.36
UniProt:
O75330
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75330
NP_036616.2
724
84100
S653
D
E
N
S
Q
L
K
S
E
V
S
K
L
R
C
Chimpanzee
Pan troglodytes
XP_001145921
725
84298
S654
D
E
N
S
Q
L
K
S
E
V
S
K
L
R
C
Rhesus Macaque
Macaca mulatta
XP_001088518
714
82407
D647
K
H
V
V
K
L
K
D
E
N
S
Q
L
K
S
Dog
Lupus familis
XP_854651
712
82189
L645
K
I
K
H
V
V
K
L
K
D
E
N
S
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q00547
794
91781
K723
Q
N
L
K
Q
K
I
K
H
V
V
K
L
K
D
Rat
Rattus norvegicus
P97779
498
57840
D431
K
H
V
V
K
L
K
D
E
N
S
Q
L
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510078
1224
143817
S1067
E
E
N
G
Q
L
K
S
E
V
S
K
L
R
S
Chicken
Gallus gallus
XP_414495
735
84777
E668
K
H
V
M
K
L
K
E
D
N
T
H
L
Q
Q
Frog
Xenopus laevis
Q91785
1388
159123
N1200
M
Q
L
C
E
T
E
N
M
R
L
E
I
Q
N
Zebra Danio
Brachydanio rerio
NP_955874
903
104691
K833
Q
N
Q
R
Q
K
I
K
H
M
V
K
L
K
E
Tiger Blowfish
Takifugu rubipres
NP_001011731
834
97660
D745
E
E
L
N
K
L
S
D
A
Y
A
R
L
L
G
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
E1434
Q
K
E
R
T
L
Q
E
E
T
S
K
L
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785252
773
89752
N690
S
E
V
N
K
L
S
N
D
Y
A
K
L
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32380
944
111763
D830
N
D
L
K
V
I
N
D
Y
L
N
K
V
L
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
94.8
85
N.A.
68.8
50.2
N.A.
36.3
49.7
21.2
33.5
26.5
22.5
N.A.
N.A.
24.3
Protein Similarity:
100
98.7
96.4
91.5
N.A.
78
57.5
N.A.
47.2
68.5
35.7
50.9
48.8
32.3
N.A.
N.A.
46.9
P-Site Identity:
100
100
33.3
6.6
N.A.
26.6
33.3
N.A.
80
20
0
20
20
33.3
N.A.
N.A.
26.6
P-Site Similarity:
100
100
53.3
26.6
N.A.
33.3
53.3
N.A.
86.6
46.6
46.6
33.3
53.3
46.6
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
15
0
0
8
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
15
% C
% Asp:
15
8
0
0
0
0
0
29
15
8
0
0
0
0
8
% D
% Glu:
15
36
8
0
8
0
8
15
43
0
8
8
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
15
% G
% His:
0
22
0
8
0
0
0
0
15
0
0
8
0
0
0
% H
% Ile:
0
8
0
0
0
8
15
0
0
0
0
0
8
0
0
% I
% Lys:
29
8
8
15
36
15
50
15
8
0
0
58
0
29
0
% K
% Leu:
0
0
29
0
0
65
0
8
0
8
8
0
79
22
8
% L
% Met:
8
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
8
15
22
15
0
0
8
15
0
22
8
8
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
22
8
8
0
36
0
8
0
0
0
0
15
0
22
8
% Q
% Arg:
0
0
0
15
0
0
0
0
0
8
0
8
0
22
0
% R
% Ser:
8
0
0
15
0
0
15
22
0
0
43
0
8
0
22
% S
% Thr:
0
0
0
0
8
8
0
0
0
8
8
0
0
0
0
% T
% Val:
0
0
29
15
15
8
0
0
0
29
15
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _