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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMMR
All Species:
9.39
Human Site:
S688
Identified Species:
15.9
UniProt:
O75330
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75330
NP_036616.2
724
84100
S688
G
I
K
H
F
D
P
S
K
A
F
H
H
E
S
Chimpanzee
Pan troglodytes
XP_001145921
725
84298
S689
G
I
K
H
F
D
P
S
K
A
F
H
H
E
S
Rhesus Macaque
Macaca mulatta
XP_001088518
714
82407
K679
K
L
Q
E
E
L
N
K
V
L
G
I
K
H
F
Dog
Lupus familis
XP_854651
712
82189
L677
E
T
K
L
Q
E
E
L
N
K
V
L
G
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q00547
794
91781
L756
R
K
Q
N
E
L
R
L
Q
G
E
L
D
K
A
Rat
Rattus norvegicus
P97779
498
57840
K463
R
L
Q
G
E
L
D
K
A
L
G
I
R
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510078
1224
143817
A1102
G
I
R
R
F
D
P
A
K
A
F
Q
H
E
S
Chicken
Gallus gallus
XP_414495
735
84777
T700
D
L
Q
E
Q
L
Y
T
I
Q
G
I
R
H
F
Frog
Xenopus laevis
Q91785
1388
159123
A1297
E
R
T
R
S
L
E
A
K
A
F
T
E
K
E
Zebra Danio
Brachydanio rerio
NP_955874
903
104691
L866
Q
K
Q
E
L
D
R
L
K
S
S
E
T
T
R
Tiger Blowfish
Takifugu rubipres
NP_001011731
834
97660
L787
L
R
S
Q
V
S
R
L
K
S
D
Q
E
Q
L
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
S1553
A
Q
M
N
G
A
S
S
R
S
G
K
G
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785252
773
89752
T723
A
S
L
K
K
E
V
T
K
L
R
E
E
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32380
944
111763
T903
E
R
R
L
S
F
K
T
V
A
L
L
V
L
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
94.8
85
N.A.
68.8
50.2
N.A.
36.3
49.7
21.2
33.5
26.5
22.5
N.A.
N.A.
24.3
Protein Similarity:
100
98.7
96.4
91.5
N.A.
78
57.5
N.A.
47.2
68.5
35.7
50.9
48.8
32.3
N.A.
N.A.
46.9
P-Site Identity:
100
100
0
6.6
N.A.
0
0
N.A.
73.3
0
20
13.3
6.6
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
13.3
N.A.
33.3
13.3
N.A.
86.6
20
33.3
26.6
20
33.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
8
0
15
8
36
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
29
8
0
0
0
8
0
8
8
0
% D
% Glu:
22
0
0
22
22
15
15
0
0
0
8
15
22
22
15
% E
% Phe:
0
0
0
0
22
8
0
0
0
0
29
0
0
0
22
% F
% Gly:
22
0
0
8
8
0
0
0
0
8
29
0
15
0
0
% G
% His:
0
0
0
15
0
0
0
0
0
0
0
15
22
22
0
% H
% Ile:
0
22
0
0
0
0
0
0
8
0
0
22
0
8
0
% I
% Lys:
8
15
22
8
8
0
8
15
50
8
0
8
8
15
8
% K
% Leu:
8
22
8
15
8
36
0
29
0
22
8
22
0
8
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
0
0
8
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
36
8
15
0
0
0
8
8
0
15
0
8
0
% Q
% Arg:
15
22
15
15
0
0
22
0
8
0
8
0
15
0
8
% R
% Ser:
0
8
8
0
15
8
8
22
0
22
8
0
0
0
22
% S
% Thr:
0
8
8
0
0
0
0
22
0
0
0
8
8
15
8
% T
% Val:
0
0
0
0
8
0
8
0
15
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _