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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMMR
All Species:
22.73
Human Site:
T179
Identified Species:
38.46
UniProt:
O75330
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75330
NP_036616.2
724
84100
T179
K
L
R
N
K
R
E
T
K
M
R
G
M
M
A
Chimpanzee
Pan troglodytes
XP_001145921
725
84298
T180
K
L
R
N
K
R
E
T
K
M
R
G
M
M
A
Rhesus Macaque
Macaca mulatta
XP_001088518
714
82407
T180
K
L
R
N
K
R
E
T
K
M
R
G
M
M
A
Dog
Lupus familis
XP_854651
712
82189
T180
K
L
R
N
K
R
E
T
K
M
R
N
M
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q00547
794
91781
T180
K
L
R
N
K
R
E
T
K
M
R
S
M
M
V
Rat
Rattus norvegicus
P97779
498
57840
R85
C
Q
L
L
E
A
E
R
D
D
L
V
S
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510078
1224
143817
A283
K
L
R
S
K
M
E
A
K
T
K
S
A
A
A
Chicken
Gallus gallus
XP_414495
735
84777
A190
K
L
R
T
K
R
D
A
K
E
K
T
A
L
A
Frog
Xenopus laevis
Q91785
1388
159123
Y607
L
A
T
S
K
Q
E
Y
E
E
F
K
E
L
T
Zebra Danio
Brachydanio rerio
NP_955874
903
104691
D188
I
E
A
K
N
K
L
D
A
K
D
K
E
L
S
Tiger Blowfish
Takifugu rubipres
NP_001011731
834
97660
T249
N
I
V
V
H
G
K
T
Q
K
E
G
L
R
R
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
A542
E
L
V
S
K
D
E
A
L
E
K
F
S
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785252
773
89752
T176
D
L
T
W
E
A
D
T
H
K
A
Q
L
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32380
944
111763
M275
E
D
E
L
K
N
L
M
N
E
L
N
E
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
94.8
85
N.A.
68.8
50.2
N.A.
36.3
49.7
21.2
33.5
26.5
22.5
N.A.
N.A.
24.3
Protein Similarity:
100
98.7
96.4
91.5
N.A.
78
57.5
N.A.
47.2
68.5
35.7
50.9
48.8
32.3
N.A.
N.A.
46.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
6.6
N.A.
46.6
46.6
13.3
0
13.3
20
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
13.3
N.A.
60
66.6
40
20
40
53.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
15
0
22
8
0
8
0
15
15
50
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
8
15
8
8
8
8
0
0
0
8
% D
% Glu:
15
8
8
0
15
0
65
0
8
29
8
0
22
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
29
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
50
0
0
8
72
8
8
0
50
22
22
15
0
8
8
% K
% Leu:
8
65
8
15
0
0
15
0
8
0
15
0
15
36
0
% L
% Met:
0
0
0
0
0
8
0
8
0
36
0
0
36
36
0
% M
% Asn:
8
0
0
36
8
8
0
0
8
0
0
15
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
8
0
0
8
0
0
0
% Q
% Arg:
0
0
50
0
0
43
0
8
0
0
36
0
0
8
8
% R
% Ser:
0
0
0
22
0
0
0
0
0
0
0
15
15
0
15
% S
% Thr:
0
0
15
8
0
0
0
50
0
8
0
8
0
0
8
% T
% Val:
0
0
15
8
0
0
0
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _