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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMMR
All Species:
23.64
Human Site:
Y625
Identified Species:
40
UniProt:
O75330
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75330
NP_036616.2
724
84100
Y625
L
N
K
I
R
D
S
Y
A
K
L
L
G
H
Q
Chimpanzee
Pan troglodytes
XP_001145921
725
84298
Y626
L
N
K
I
R
D
S
Y
A
K
L
L
G
H
Q
Rhesus Macaque
Macaca mulatta
XP_001088518
714
82407
Y626
L
N
K
I
R
D
S
Y
A
K
L
L
G
H
Q
Dog
Lupus familis
XP_854651
712
82189
Y626
L
N
K
L
R
D
S
Y
A
K
L
L
G
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q00547
794
91781
Q699
L
N
E
H
G
A
T
Q
E
Q
L
N
K
I
R
Rat
Rattus norvegicus
P97779
498
57840
Q412
K
I
R
D
S
Y
A
Q
L
L
G
H
Q
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510078
1224
143817
Y1039
L
T
K
L
S
E
S
Y
A
K
L
L
G
H
Q
Chicken
Gallus gallus
XP_414495
735
84777
Y647
L
N
K
L
S
E
A
Y
A
K
L
L
G
H
Q
Frog
Xenopus laevis
Q91785
1388
159123
N1169
N
L
Q
K
R
N
T
N
L
E
I
L
V
S
E
Zebra Danio
Brachydanio rerio
NP_955874
903
104691
Q809
L
N
E
K
G
A
T
Q
A
E
L
N
K
L
A
Tiger Blowfish
Takifugu rubipres
NP_001011731
834
97660
R704
V
D
Q
A
Q
E
K
R
W
E
K
V
R
I
Y
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
Q1279
T
S
C
L
K
E
T
Q
D
Q
L
L
E
S
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785252
773
89752
R671
L
N
Q
F
E
M
D
R
R
M
L
L
S
Q
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32380
944
111763
T776
K
N
Y
L
S
E
I
T
S
L
Q
E
E
N
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
94.8
85
N.A.
68.8
50.2
N.A.
36.3
49.7
21.2
33.5
26.5
22.5
N.A.
N.A.
24.3
Protein Similarity:
100
98.7
96.4
91.5
N.A.
78
57.5
N.A.
47.2
68.5
35.7
50.9
48.8
32.3
N.A.
N.A.
46.9
P-Site Identity:
100
100
100
93.3
N.A.
20
0
N.A.
73.3
73.3
13.3
26.6
0
20
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
46.6
20
N.A.
86.6
93.3
53.3
46.6
46.6
60
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
15
15
0
50
0
0
0
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
29
8
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
15
0
8
36
0
0
8
22
0
8
15
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
0
0
0
0
0
8
0
43
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
0
43
0
% H
% Ile:
0
8
0
22
0
0
8
0
0
0
8
0
0
15
0
% I
% Lys:
15
0
43
15
8
0
8
0
0
43
8
0
15
0
0
% K
% Leu:
65
8
0
36
0
0
0
0
15
15
72
65
0
8
8
% L
% Met:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
65
0
0
0
8
0
8
0
0
0
15
0
15
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
22
0
8
0
0
29
0
15
8
0
8
8
50
% Q
% Arg:
0
0
8
0
36
0
0
15
8
0
0
0
8
0
15
% R
% Ser:
0
8
0
0
29
0
36
0
8
0
0
0
8
15
0
% S
% Thr:
8
8
0
0
0
0
29
8
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
43
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _