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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPFIA2
All Species:
21.82
Human Site:
S349
Identified Species:
48
UniProt:
O75334
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75334
NP_003616.2
1257
143142
S349
T
L
E
K
R
Y
L
S
A
Q
R
E
S
T
S
Chimpanzee
Pan troglodytes
XP_508612
1335
150142
A463
T
L
E
K
R
Y
L
A
A
Q
R
E
A
T
S
Rhesus Macaque
Macaca mulatta
XP_001088353
1247
142080
S349
T
L
E
K
R
Y
L
S
A
Q
R
E
S
T
S
Dog
Lupus familis
XP_532638
1177
134127
K323
K
L
Q
Q
T
M
R
K
A
E
T
L
P
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSS9
1257
143216
S349
T
L
E
K
R
Y
L
S
A
Q
R
E
S
T
S
Rat
Rattus norvegicus
Q91Z79
1192
133411
Q342
S
K
E
S
L
Y
R
Q
S
E
E
K
S
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505810
1257
143115
S349
T
L
E
K
R
Y
L
S
A
Q
R
E
S
T
S
Chicken
Gallus gallus
XP_416120
1253
142576
S349
T
L
E
K
R
Y
L
S
A
Q
R
E
S
T
S
Frog
Xenopus laevis
NP_001088956
1208
136964
A331
T
L
E
K
R
Y
L
A
A
Q
R
E
S
T
S
Zebra Danio
Brachydanio rerio
A9C3W3
786
88912
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21049
1139
130316
T321
T
F
E
S
R
F
L
T
A
Q
R
E
S
T
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.5
98.3
89.8
N.A.
98.4
59.7
N.A.
96.6
94.4
66.8
20.8
N.A.
N.A.
N.A.
41
N.A.
Protein Similarity:
100
74.5
98.5
91
N.A.
98.9
73.5
N.A.
98.4
96.9
79.6
35.2
N.A.
N.A.
N.A.
57.8
N.A.
P-Site Identity:
100
86.6
100
13.3
N.A.
100
20
N.A.
100
100
93.3
0
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
100
46.6
N.A.
100
100
100
0
N.A.
N.A.
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
19
82
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
82
0
0
0
0
0
0
19
10
73
0
10
0
% E
% Phe:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
0
64
0
0
0
10
0
0
0
10
0
0
0
% K
% Leu:
0
73
0
0
10
0
73
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
10
10
0
0
0
10
0
73
0
0
0
0
10
% Q
% Arg:
0
0
0
0
73
0
19
0
0
0
73
0
0
10
0
% R
% Ser:
10
0
0
19
0
0
0
46
10
0
0
0
73
0
64
% S
% Thr:
73
0
0
0
10
0
0
10
0
0
10
0
0
73
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
73
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _