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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD6
All Species:
29.09
Human Site:
S127
Identified Species:
49.23
UniProt:
O75340
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75340
NP_037364.1
191
21868
S127
S
G
F
G
Y
R
L
S
D
Q
F
H
D
I
L
Chimpanzee
Pan troglodytes
XP_527191
191
22034
S127
S
G
F
G
Y
R
L
S
D
Q
F
H
D
I
L
Rhesus Macaque
Macaca mulatta
XP_001119112
174
19925
Q128
F
D
R
Q
G
R
G
Q
I
A
F
D
D
F
I
Dog
Lupus familis
XP_851917
189
21695
S125
S
G
F
G
Y
R
L
S
D
Q
F
H
D
I
L
Cat
Felis silvestris
Mouse
Mus musculus
P12815
191
21849
S127
S
G
F
G
Y
R
L
S
D
Q
F
H
D
I
L
Rat
Rattus norvegicus
Q641Z8
283
29994
S217
S
Q
M
G
Y
N
L
S
P
Q
F
T
Q
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513705
313
35244
S171
S
G
F
G
Y
R
L
S
D
Q
F
H
D
I
L
Chicken
Gallus gallus
XP_419075
178
20703
I122
D
Q
F
Y
D
T
L
I
R
K
F
D
R
Q
G
Frog
Xenopus laevis
Q5PQ53
283
30514
S217
C
Q
M
G
Y
Q
L
S
P
Q
F
V
Q
I
V
Zebra Danio
Brachydanio rerio
Q6DC93
270
29406
S204
S
Q
M
G
Y
N
L
S
P
Q
F
I
Q
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001104459
178
20747
D125
D
V
L
L
R
K
F
D
R
F
G
R
G
T
I
Honey Bee
Apis mellifera
XP_392209
177
20591
R128
R
K
Y
D
R
A
G
R
G
T
I
Y
F
D
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176285
173
19986
S122
L
I
R
K
F
D
R
S
G
K
G
S
I
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4L0
335
35283
S267
M
S
L
G
F
S
V
S
P
V
I
L
D
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
71.7
97.9
N.A.
98.9
31.1
N.A.
49.5
84.8
31.4
27
N.A.
62.8
60.2
N.A.
60.2
Protein Similarity:
100
95.2
74.8
97.9
N.A.
98.9
43.1
N.A.
53.6
88.4
44.8
41.4
N.A.
73.8
72.2
N.A.
74.8
P-Site Identity:
100
100
20
100
N.A.
100
53.3
N.A.
100
20
46.6
53.3
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
60
N.A.
100
26.6
60
53.3
N.A.
13.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
8
0
8
8
8
0
8
36
0
0
15
50
8
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
8
0
43
0
15
0
8
0
0
8
72
0
8
8
8
% F
% Gly:
0
36
0
65
8
0
15
0
15
0
15
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
36
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
8
0
15
8
8
43
15
% I
% Lys:
0
8
0
8
0
8
0
0
0
15
0
0
0
0
0
% K
% Leu:
8
0
15
8
0
0
65
0
0
0
0
8
0
15
58
% L
% Met:
8
0
22
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
29
0
0
0
0
0
0
% P
% Gln:
0
29
0
8
0
8
0
8
0
58
0
0
22
8
0
% Q
% Arg:
8
0
15
0
15
43
8
8
15
0
0
8
8
0
0
% R
% Ser:
50
8
0
0
0
8
0
72
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
0
8
0
8
0
% T
% Val:
0
8
0
0
0
0
8
0
0
8
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
58
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _