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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD6
All Species:
23.64
Human Site:
Y168
Identified Species:
40
UniProt:
O75340
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75340
NP_037364.1
191
21868
Y168
L
T
D
I
F
R
R
Y
D
T
D
Q
D
G
W
Chimpanzee
Pan troglodytes
XP_527191
191
22034
Y168
L
T
D
I
F
R
R
Y
D
T
D
Q
D
G
W
Rhesus Macaque
Macaca mulatta
XP_001119112
174
19925
Y151
L
T
D
I
F
R
R
Y
D
T
D
Q
D
G
W
Dog
Lupus familis
XP_851917
189
21695
Y166
L
T
D
I
F
R
R
Y
D
T
D
Q
D
G
W
Cat
Felis silvestris
Mouse
Mus musculus
P12815
191
21849
Y168
L
T
D
I
F
R
R
Y
D
T
D
Q
D
G
W
Rat
Rattus norvegicus
Q641Z8
283
29994
K259
L
T
E
A
F
R
E
K
D
T
A
V
Q
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513705
313
35244
T212
E
R
A
I
V
P
E
T
I
I
Q
R
E
R
H
Chicken
Gallus gallus
XP_419075
178
20703
Y155
L
T
D
V
F
R
R
Y
D
T
D
Q
D
G
W
Frog
Xenopus laevis
Q5PQ53
283
30514
K259
M
T
E
A
F
R
E
K
D
T
G
Q
I
G
T
Zebra Danio
Brachydanio rerio
Q6DC93
270
29406
K246
M
T
Q
A
F
R
E
K
D
T
G
M
T
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001104459
178
20747
H154
L
T
T
A
F
R
Q
H
D
T
D
L
D
G
I
Honey Bee
Apis mellifera
XP_392209
177
20591
L153
L
T
A
A
F
R
Q
L
D
T
D
L
D
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176285
173
19986
F149
L
T
N
S
F
Q
G
F
D
T
N
R
N
G
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4L0
335
35283
K310
L
T
E
K
F
K
E
K
D
T
A
L
S
G
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
71.7
97.9
N.A.
98.9
31.1
N.A.
49.5
84.8
31.4
27
N.A.
62.8
60.2
N.A.
60.2
Protein Similarity:
100
95.2
74.8
97.9
N.A.
98.9
43.1
N.A.
53.6
88.4
44.8
41.4
N.A.
73.8
72.2
N.A.
74.8
P-Site Identity:
100
100
100
100
N.A.
100
46.6
N.A.
6.6
93.3
46.6
40
N.A.
60
60
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
53.3
N.A.
20
100
60
46.6
N.A.
73.3
66.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
36
0
0
0
0
0
0
15
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
43
0
0
0
0
0
93
0
58
0
58
0
0
% D
% Glu:
8
0
22
0
0
0
36
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
93
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
15
0
0
93
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
43
0
0
0
0
8
8
0
0
8
0
8
% I
% Lys:
0
0
0
8
0
8
0
29
0
0
0
0
0
0
0
% K
% Leu:
79
0
0
0
0
0
0
8
0
0
0
22
0
0
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
8
0
8
0
15
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
8
15
0
0
0
8
50
8
0
0
% Q
% Arg:
0
8
0
0
0
79
43
0
0
0
0
15
0
8
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
8
% S
% Thr:
0
93
8
0
0
0
0
8
0
93
0
0
8
0
8
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% W
% Tyr:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _