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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALOX12B All Species: 16.97
Human Site: Y156 Identified Species: 37.33
UniProt: O75342 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75342 NP_001130.1 701 80356 Y156 F L P G L P S Y V H I P S Y R
Chimpanzee Pan troglodytes XP_511864 701 80411 Y156 F L P G L P S Y V H I P S Y R
Rhesus Macaque Macaca mulatta XP_001111929 711 80558 M156 Y A P G F P R M V D V N S F Q
Dog Lupus familis XP_546604 699 80232 Y156 F V P G L P N Y V H I P S Y R
Cat Felis silvestris
Mouse Mus musculus O70582 701 80559 Y156 F V P G L P N Y V D I P S Y H
Rat Rattus norvegicus Q2KMM4 701 80722 Y156 F V P G L P N Y V D I P S Y H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517706 444 51126
Chicken Gallus gallus XP_423676 651 74206 W148 W K N Y A E G W P R C L S V D
Frog Xenopus laevis NP_001089265 670 75862 A150 T H K W K T Y A V G V P R C I
Zebra Danio Brachydanio rerio NP_955912 670 76988 A149 T Y R W V A W A P G I P K C I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LNR3 919 103708 H343 G R L K A V L H H L I P S L K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 54.2 88.1 N.A. 86 86.5 N.A. 44 47.5 44.9 40.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 72.2 96 N.A. 94 94.1 N.A. 51 64.7 64.3 59 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 33.3 86.6 N.A. 73.3 73.3 N.A. 0 6.6 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 60 100 N.A. 86.6 86.6 N.A. 0 20 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 19 10 0 19 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 19 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 28 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 46 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 10 0 0 55 0 0 10 0 0 19 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 10 10 28 0 0 0 0 19 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 64 0 0 0 19 % I
% Lys: 0 10 10 10 10 0 0 0 0 0 0 0 10 0 10 % K
% Leu: 0 19 10 0 46 0 10 0 0 10 0 10 0 10 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 28 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 55 0 0 55 0 0 19 0 0 73 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 10 10 0 0 0 10 0 0 10 0 0 10 0 28 % R
% Ser: 0 0 0 0 0 0 19 0 0 0 0 0 73 0 0 % S
% Thr: 19 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % T
% Val: 0 28 0 0 10 10 0 0 64 0 19 0 0 10 0 % V
% Trp: 10 0 0 19 0 0 10 10 0 0 0 0 0 0 0 % W
% Tyr: 10 10 0 10 0 0 10 46 0 0 0 0 0 46 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _