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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP6 All Species: 20.3
Human Site: S205 Identified Species: 44.67
UniProt: O75344 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75344 NP_003593.3 327 37214 S205 L L L L R R R S A P P E E Q H
Chimpanzee Pan troglodytes XP_527778 399 45368 S277 L L L L R R R S A P P E E Q H
Rhesus Macaque Macaca mulatta XP_001110932 327 37177 S205 L L L L R R R S A P S E A Q H
Dog Lupus familis XP_546928 327 37501 S205 L L L L H R R S A P P E E Q H
Cat Felis silvestris
Mouse Mus musculus Q91XW8 327 37106 L205 L L L L H R R L A T C E E Q H
Rat Rattus norvegicus Q9QVC8 458 51432 S304 V S W L E Y E S S F S G E E M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519210 339 38712 S218 S V I L N R Q S A S P E E Q E
Chicken Gallus gallus XP_415708 264 30195 A178 Y L K L E S P A R A L M Y G E
Frog Xenopus laevis NP_001085204 304 34896 S193 K A S C D E E S K L L E A A Q
Zebra Danio Brachydanio rerio NP_001122145 343 39215 E211 M T L L Q N R E P E D A E E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001149790 553 61673 T437 A K Y I E Y D T S F S E D E K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.6 96.6 89.3 N.A. 84.4 25.5 N.A. 69.3 54.7 60.5 48 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 80.9 97.5 93.2 N.A. 89.5 40.1 N.A. 81.7 65.7 75.2 67.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 93.3 N.A. 73.3 20 N.A. 53.3 13.3 13.3 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 93.3 N.A. 73.3 40 N.A. 73.3 20 13.3 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 20 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 35.4 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 40 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 10 55 10 0 10 19 10 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 10 0 0 0 10 0 10 0 0 % D
% Glu: 0 0 0 0 28 10 19 10 0 10 0 73 64 28 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % G
% His: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 46 % H
% Ile: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 10 10 0 0 0 0 0 10 0 0 0 0 0 19 % K
% Leu: 46 55 55 82 0 0 0 10 0 10 19 0 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % M
% Asn: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 10 37 37 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 10 0 0 0 0 0 0 55 10 % Q
% Arg: 0 0 0 0 28 55 55 0 10 0 0 0 0 0 0 % R
% Ser: 10 10 10 0 0 10 0 64 19 10 28 0 0 0 0 % S
% Thr: 0 10 0 0 0 0 0 10 0 10 0 0 0 0 0 % T
% Val: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 0 0 19 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _