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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCA
All Species:
50.61
Human Site:
Y26
Identified Species:
79.52
UniProt:
O75347
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75347
NP_004598.1
108
12855
Y26
L
V
K
E
K
V
M
Y
E
K
E
A
K
Q
Q
Chimpanzee
Pan troglodytes
XP_520997
108
12749
Y26
L
V
K
E
K
V
M
Y
E
K
E
A
K
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001111237
108
12869
Y26
L
V
K
E
K
V
M
Y
E
K
E
A
K
Q
Q
Dog
Lupus familis
XP_536315
92
10924
I21
A
K
Q
Q
E
E
K
I
E
K
M
K
A
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P48428
108
12739
Y26
L
V
K
E
R
V
M
Y
E
K
E
A
K
Q
Q
Rat
Rattus norvegicus
Q6PEC1
108
12725
Y26
L
V
K
E
K
V
M
Y
E
K
E
A
K
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514135
148
17028
Y66
L
V
K
E
K
L
M
Y
E
K
E
A
K
Q
Q
Chicken
Gallus gallus
P80585
108
12660
Y26
L
A
K
E
K
V
M
Y
E
K
E
A
K
Q
Q
Frog
Xenopus laevis
NP_001085368
108
12767
Y26
L
A
K
E
K
I
M
Y
E
K
E
A
I
Q
Q
Zebra Danio
Brachydanio rerio
NP_957348
108
12605
Y26
L
A
K
E
E
V
L
Y
I
K
E
A
K
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651885
110
12924
Y26
L
T
R
E
K
Y
C
Y
A
K
E
V
L
T
E
Honey Bee
Apis mellifera
XP_396381
118
13936
Y26
L
A
K
E
K
V
T
Y
E
K
E
A
A
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002319219
115
13025
Y26
I
V
K
E
L
R
S
Y
E
K
E
I
E
R
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04350
113
12806
Y24
I
V
K
E
L
H
S
Y
E
K
E
V
E
R
E
Baker's Yeast
Sacchar. cerevisiae
P48606
106
12360
Y23
L
T
K
E
E
G
Y
Y
Q
Q
E
L
K
D
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
95.3
77.7
N.A.
92.5
93.5
N.A.
62.1
83.3
78.6
75
N.A.
42.7
55
N.A.
N.A.
Protein Similarity:
100
100
97.2
82.4
N.A.
98.1
98.1
N.A.
69.5
92.5
89.8
87
N.A.
70
75.4
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
93.3
100
N.A.
93.3
93.3
80
73.3
N.A.
40
80
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
100
93.3
86.6
86.6
N.A.
53.3
80
N.A.
N.A.
Percent
Protein Identity:
44.3
N.A.
N.A.
43.3
27.7
N.A.
Protein Similarity:
62.6
N.A.
N.A.
61
56.4
N.A.
P-Site Identity:
46.6
N.A.
N.A.
46.6
46.6
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
73.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
27
0
0
0
0
0
0
7
0
0
67
14
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% D
% Glu:
0
0
0
94
20
7
0
0
80
0
94
0
14
7
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
0
0
0
0
7
0
7
7
0
0
7
7
0
0
% I
% Lys:
0
7
87
0
60
0
7
0
0
94
0
7
60
0
0
% K
% Leu:
80
0
0
0
14
7
7
0
0
0
0
7
7
0
0
% L
% Met:
0
0
0
0
0
0
54
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
7
0
0
0
0
7
7
0
0
0
67
74
% Q
% Arg:
0
0
7
0
7
7
0
0
0
0
0
0
0
14
0
% R
% Ser:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% S
% Thr:
0
14
0
0
0
0
7
0
0
0
0
0
0
7
0
% T
% Val:
0
54
0
0
0
54
0
0
0
0
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
7
94
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _