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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCA
All Species:
43.33
Human Site:
Y48
Identified Species:
68.1
UniProt:
O75347
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75347
NP_004598.1
108
12855
Y48
R
A
E
D
G
E
N
Y
D
I
K
K
Q
A
E
Chimpanzee
Pan troglodytes
XP_520997
108
12749
Y48
R
A
E
D
G
E
N
Y
D
I
K
K
Q
A
E
Rhesus Macaque
Macaca mulatta
XP_001111237
108
12869
Y48
R
A
E
D
G
E
N
Y
D
I
K
K
Q
V
E
Dog
Lupus familis
XP_536315
92
10924
K36
G
E
N
Y
A
I
K
K
Q
A
E
I
L
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
P48428
108
12739
Y48
K
A
E
D
G
E
N
Y
A
I
K
K
Q
A
E
Rat
Rattus norvegicus
Q6PEC1
108
12725
Y48
K
A
E
D
G
E
N
Y
A
I
K
K
Q
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514135
148
17028
Y88
K
A
E
D
G
E
N
Y
N
I
K
K
Q
T
E
Chicken
Gallus gallus
P80585
108
12660
Y48
K
A
E
A
C
D
D
Y
G
I
K
K
Q
A
E
Frog
Xenopus laevis
NP_001085368
108
12767
Y48
K
S
E
G
G
D
E
Y
V
I
K
K
Q
I
E
Zebra Danio
Brachydanio rerio
NP_957348
108
12605
Y48
K
A
E
A
G
D
E
Y
L
I
K
K
Q
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651885
110
12924
H48
R
G
D
G
A
D
D
H
V
L
R
K
Q
E
E
Honey Bee
Apis mellifera
XP_396381
118
13936
Y48
K
E
Q
D
K
D
G
Y
D
I
K
K
Q
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002319219
115
13025
Y48
K
D
K
G
A
D
P
Y
D
L
K
Q
Q
E
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04350
113
12806
Y46
K
D
K
G
A
D
P
Y
D
L
K
Q
Q
E
N
Baker's Yeast
Sacchar. cerevisiae
P48606
106
12360
Y46
E
D
K
S
V
D
P
Y
D
L
K
K
Q
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
95.3
77.7
N.A.
92.5
93.5
N.A.
62.1
83.3
78.6
75
N.A.
42.7
55
N.A.
N.A.
Protein Similarity:
100
100
97.2
82.4
N.A.
98.1
98.1
N.A.
69.5
92.5
89.8
87
N.A.
70
75.4
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
86.6
86.6
N.A.
80
60
53.3
60
N.A.
26.6
53.3
N.A.
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
93.3
93.3
N.A.
93.3
80
73.3
73.3
N.A.
66.6
73.3
N.A.
N.A.
Percent
Protein Identity:
44.3
N.A.
N.A.
43.3
27.7
N.A.
Protein Similarity:
62.6
N.A.
N.A.
61
56.4
N.A.
P-Site Identity:
26.6
N.A.
N.A.
26.6
40
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
14
27
0
0
0
14
7
0
0
0
34
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
7
47
0
54
14
0
47
0
0
0
0
0
0
% D
% Glu:
7
14
60
0
0
40
14
0
0
0
7
0
0
34
87
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
0
27
54
0
7
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
67
0
7
0
7
0
% I
% Lys:
60
0
20
0
7
0
7
7
0
0
87
80
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
7
27
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
7
0
0
0
40
0
7
0
0
0
0
0
14
% N
% Pro:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
7
0
0
14
94
7
0
% Q
% Arg:
27
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
0
0
0
0
7
0
0
0
14
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _