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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCA
All Species:
24.24
Human Site:
Y75
Identified Species:
38.1
UniProt:
O75347
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75347
NP_004598.1
108
12855
Y75
Q
R
R
L
E
A
A
Y
L
D
L
Q
R
I
L
Chimpanzee
Pan troglodytes
XP_520997
108
12749
Y75
Q
R
R
L
E
A
A
Y
L
D
L
Q
Q
I
L
Rhesus Macaque
Macaca mulatta
XP_001111237
108
12869
Y75
Q
R
R
L
E
A
A
Y
L
D
L
Q
Q
I
L
Dog
Lupus familis
XP_536315
92
10924
L63
E
A
A
Y
T
D
L
L
Q
L
L
E
S
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P48428
108
12739
Y75
Q
R
R
L
E
A
A
Y
T
D
L
Q
Q
I
L
Rat
Rattus norvegicus
Q6PEC1
108
12725
Y75
Q
R
R
L
E
A
A
Y
T
D
L
R
Q
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514135
148
17028
H115
Q
R
R
L
E
A
A
H
S
D
L
L
Q
L
L
Chicken
Gallus gallus
P80585
108
12660
H75
Q
R
R
L
E
I
A
H
A
D
L
T
Q
L
L
Frog
Xenopus laevis
NP_001085368
108
12767
Y75
H
R
R
L
E
A
A
Y
A
D
L
T
Q
L
L
Zebra Danio
Brachydanio rerio
NP_957348
108
12605
H75
H
R
R
L
A
M
A
H
A
D
L
Q
Q
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651885
110
12924
Y75
K
R
R
L
Q
K
E
Y
E
V
L
E
K
Y
L
Honey Bee
Apis mellifera
XP_396381
118
13936
F75
Q
R
R
L
A
K
A
F
E
E
L
K
K
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002319219
115
13025
L75
R
K
R
L
E
A
A
L
A
D
L
K
A
I
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04350
113
12806
L73
H
K
R
L
E
S
A
L
A
D
L
K
S
T
L
Baker's Yeast
Sacchar. cerevisiae
P48606
106
12360
K73
Y
E
K
I
R
E
F
K
E
D
L
E
Q
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
95.3
77.7
N.A.
92.5
93.5
N.A.
62.1
83.3
78.6
75
N.A.
42.7
55
N.A.
N.A.
Protein Similarity:
100
100
97.2
82.4
N.A.
98.1
98.1
N.A.
69.5
92.5
89.8
87
N.A.
70
75.4
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
6.6
N.A.
86.6
80
N.A.
66.6
60
66.6
53.3
N.A.
40
53.3
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
93.3
N.A.
86.6
80
80
73.3
N.A.
66.6
80
N.A.
N.A.
Percent
Protein Identity:
44.3
N.A.
N.A.
43.3
27.7
N.A.
Protein Similarity:
62.6
N.A.
N.A.
61
56.4
N.A.
P-Site Identity:
60
N.A.
N.A.
46.6
20
N.A.
P-Site Similarity:
80
N.A.
N.A.
66.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
14
54
80
0
34
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
80
0
0
0
0
0
% D
% Glu:
7
7
0
0
67
7
7
0
20
7
0
20
0
7
0
% E
% Phe:
0
0
0
0
0
0
7
7
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
20
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
7
0
0
0
0
0
0
0
47
0
% I
% Lys:
7
14
7
0
0
14
0
7
0
0
0
20
14
0
7
% K
% Leu:
0
0
0
87
0
0
7
20
20
7
100
7
0
27
94
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
54
0
0
0
7
0
0
0
7
0
0
34
60
0
0
% Q
% Arg:
7
74
87
0
7
0
0
0
0
0
0
7
7
0
0
% R
% Ser:
0
0
0
0
0
7
0
0
7
0
0
0
14
0
0
% S
% Thr:
0
0
0
0
7
0
0
0
14
0
0
14
0
7
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
0
47
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _