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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS4B
All Species:
16.89
Human Site:
T4
Identified Species:
28.58
UniProt:
O75351
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75351
NP_004860.2
444
49302
T4
_
_
_
_
M
S
S
T
S
P
N
L
Q
K
A
Chimpanzee
Pan troglodytes
XP_001146376
412
45621
T4
_
_
_
_
M
S
S
T
S
P
N
L
Q
K
A
Rhesus Macaque
Macaca mulatta
XP_001093648
516
56751
T81
A
D
P
G
D
E
M
T
T
S
T
L
Q
K
A
Dog
Lupus familis
XP_848812
444
49189
T4
_
_
_
_
M
A
S
T
S
A
N
F
Q
K
A
Cat
Felis silvestris
Mouse
Mus musculus
P46467
444
49401
T4
_
_
_
_
M
A
S
T
N
T
N
L
Q
K
A
Rat
Rattus norvegicus
Q5XIK7
488
55183
Y16
N
A
K
K
G
R
E
Y
A
L
L
G
N
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510255
484
54482
L49
R
V
K
W
R
E
A
L
G
G
D
L
K
K
A
Chicken
Gallus gallus
Q1HGK7
492
56020
V10
L
V
M
I
S
E
N
V
K
L
A
R
E
Y
A
Frog
Xenopus laevis
Q9PUL2
486
55412
M5
_
_
_
M
S
L
L
M
I
S
E
N
V
K
L
Zebra Danio
Brachydanio rerio
Q5U3S1
488
54873
A10
L
T
E
I
C
D
N
A
K
K
G
R
E
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393250
441
49311
A10
S
G
T
I
L
Q
K
A
I
D
L
V
T
R
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O61577
516
57575
E5
_
_
_
M
S
V
D
E
I
C
E
N
T
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
S4
_
_
_
_
M
V
G
S
S
N
S
L
A
G
L
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
G10
T
G
D
F
L
T
K
G
I
E
L
V
Q
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.7
70.1
96.4
N.A.
95.5
35.2
N.A.
74.1
36.3
36.4
36.4
N.A.
N.A.
75.9
N.A.
34.8
Protein Similarity:
100
92.7
79
97.5
N.A.
97.3
54.9
N.A.
83.4
54.2
54.1
54.9
N.A.
N.A.
87.8
N.A.
53.1
P-Site Identity:
100
100
33.3
72.7
N.A.
72.7
0
N.A.
20
6.6
8.3
6.6
N.A.
N.A.
6.6
N.A.
8.3
P-Site Similarity:
100
100
46.6
81.8
N.A.
90.9
6.6
N.A.
40
26.6
8.3
26.6
N.A.
N.A.
40
N.A.
8.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.5
61
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.1
74.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
27.2
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
45.4
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
15
8
15
8
8
8
0
8
0
72
% A
% Cys:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
8
8
0
0
8
8
0
0
0
8
% D
% Glu:
0
0
8
0
0
22
8
8
0
8
15
0
15
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
15
0
8
8
0
8
8
8
8
8
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
22
0
0
0
0
29
0
0
0
0
0
0
% I
% Lys:
0
0
15
8
0
0
15
0
15
8
0
0
8
65
0
% K
% Leu:
15
0
0
0
15
8
8
8
0
15
22
43
0
0
15
% L
% Met:
0
0
8
15
36
0
8
8
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
0
0
15
0
8
8
29
15
8
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
15
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
43
0
0
% Q
% Arg:
8
0
0
0
8
8
0
0
0
0
0
15
0
8
0
% R
% Ser:
8
0
0
0
22
15
29
8
29
15
8
0
0
0
0
% S
% Thr:
8
8
8
0
0
8
0
36
8
8
8
0
15
0
0
% T
% Val:
0
15
0
0
0
15
0
8
0
0
0
15
8
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
22
0
% Y
% Spaces:
50
50
50
36
0
0
0
0
0
0
0
0
0
0
0
% _