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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPDU1 All Species: 43.33
Human Site: S43 Identified Species: 86.67
UniProt: O75352 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75352 NP_004861.2 247 26638 S43 P C L K I L L S K G L G L G I
Chimpanzee Pan troglodytes XP_001171651 259 27428 S43 P C L K I L L S K G L G L G I
Rhesus Macaque Macaca mulatta XP_001110171 247 26676 S43 P C L K I L L S K G L G L G I
Dog Lupus familis XP_546595 246 26708 S43 P C L K I L L S K S L G L G I
Cat Felis silvestris
Mouse Mus musculus Q9R0Q9 247 26479 S43 P C L K I L L S K G L G L G I
Rat Rattus norvegicus NP_001100481 247 26529 S43 P C L K I L L S K G L G L G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002130 255 27665 S50 D C L K I V I S K G L G I G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMW8 252 27527 S38 P C F K A L L S K G L G L A I
Honey Bee Apis mellifera XP_393909 244 26944 S38 G C F K S T L S K V L G L G I
Nematode Worm Caenorhab. elegans Q20157 238 25582 S34 T C P K A V L S R G L G F A I
Sea Urchin Strong. purpuratus XP_796740 252 27486 S44 P C L K V A L S K G L G L G I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LTI3 239 26400 S31 D C L L P L I S K L L G Y F L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71 98.7 89.4 N.A. 91 88.6 N.A. N.A. N.A. N.A. 67 N.A. 47.6 51 38.4 54.3
Protein Similarity: 100 76.4 100 93.9 N.A. 94.7 93.5 N.A. N.A. N.A. N.A. 83.1 N.A. 67.8 66.4 58.2 72.6
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. N.A. N.A. 73.3 N.A. 80 66.6 53.3 86.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. N.A. N.A. 93.3 N.A. 80 66.6 66.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. 33.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 9 0 0 0 0 0 0 0 17 0 % A
% Cys: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 17 0 0 0 0 0 0 0 0 0 9 9 0 % F
% Gly: 9 0 0 0 0 0 0 0 0 75 0 100 0 75 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 59 0 17 0 0 0 0 0 9 0 92 % I
% Lys: 0 0 0 92 0 0 0 0 92 0 0 0 0 0 0 % K
% Leu: 0 0 75 9 0 67 84 0 0 9 100 0 75 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 67 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 9 0 0 100 0 9 0 0 0 0 0 % S
% Thr: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 9 17 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _