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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPDU1 All Species: 31.82
Human Site: T175 Identified Species: 63.64
UniProt: O75352 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75352 NP_004861.2 247 26638 T175 G R L L Q A A T N Y H N G H T
Chimpanzee Pan troglodytes XP_001171651 259 27428 K175 G R V G T R S K G Q D V G G A
Rhesus Macaque Macaca mulatta XP_001110171 247 26676 T175 G R L L Q A A T N Y H N G H T
Dog Lupus familis XP_546595 246 26708 T175 G R L I Q A A T N Y Q N G H T
Cat Felis silvestris
Mouse Mus musculus Q9R0Q9 247 26479 T175 G K L L Q A A T N Y R N G H T
Rat Rattus norvegicus NP_001100481 247 26529 T175 G K L L Q A A T N Y H N G H T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002130 255 27665 T182 G R L I Q A G T N Y R N G H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMW8 252 27527 T170 G K L S Q A Y T N Y Q A G S T
Honey Bee Apis mellifera XP_393909 244 26944 T170 S K L I Q A Y T N Y T N G N T
Nematode Worm Caenorhab. elegans Q20157 238 25582 Q166 S K L L Q I S Q N Y R A Q S T
Sea Urchin Strong. purpuratus XP_796740 252 27486 T176 S K L I Q A Y T N F S N G H T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LTI3 239 26400 K164 A R I P Q I W K N F R N K S T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71 98.7 89.4 N.A. 91 88.6 N.A. N.A. N.A. N.A. 67 N.A. 47.6 51 38.4 54.3
Protein Similarity: 100 76.4 100 93.9 N.A. 94.7 93.5 N.A. N.A. N.A. N.A. 83.1 N.A. 67.8 66.4 58.2 72.6
P-Site Identity: 100 20 100 86.6 N.A. 86.6 93.3 N.A. N.A. N.A. N.A. 80 N.A. 60 60 40 60
P-Site Similarity: 100 33.3 100 93.3 N.A. 93.3 100 N.A. N.A. N.A. N.A. 86.6 N.A. 66.6 80 53.3 80
Percent
Protein Identity: N.A. N.A. N.A. 33.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 75 42 0 0 0 0 17 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % F
% Gly: 67 0 0 9 0 0 9 0 9 0 0 0 84 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 25 0 0 59 0 % H
% Ile: 0 0 9 34 0 17 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 50 0 0 0 0 0 17 0 0 0 0 9 0 0 % K
% Leu: 0 0 84 42 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 92 0 0 75 0 9 0 % N
% Pro: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 92 0 0 9 0 9 17 0 9 0 0 % Q
% Arg: 0 50 0 0 0 9 0 0 0 0 34 0 0 0 0 % R
% Ser: 25 0 0 9 0 0 17 0 0 0 9 0 0 25 0 % S
% Thr: 0 0 0 0 9 0 0 75 0 0 9 0 0 0 92 % T
% Val: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 25 0 0 75 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _