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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPDU1 All Species: 31.21
Human Site: Y177 Identified Species: 62.42
UniProt: O75352 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75352 NP_004861.2 247 26638 Y177 L L Q A A T N Y H N G H T G Q
Chimpanzee Pan troglodytes XP_001171651 259 27428 Q177 V G T R S K G Q D V G G A G W
Rhesus Macaque Macaca mulatta XP_001110171 247 26676 Y177 L L Q A A T N Y H N G H T G Q
Dog Lupus familis XP_546595 246 26708 Y177 L I Q A A T N Y Q N G H T G Q
Cat Felis silvestris
Mouse Mus musculus Q9R0Q9 247 26479 Y177 L L Q A A T N Y R N G H T G Q
Rat Rattus norvegicus NP_001100481 247 26529 Y177 L L Q A A T N Y H N G H T G Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002130 255 27665 Y184 L I Q A G T N Y R N G H T G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMW8 252 27527 Y172 L S Q A Y T N Y Q A G S T G Q
Honey Bee Apis mellifera XP_393909 244 26944 Y172 L I Q A Y T N Y T N G N T G Q
Nematode Worm Caenorhab. elegans Q20157 238 25582 Y168 L L Q I S Q N Y R A Q S T G Q
Sea Urchin Strong. purpuratus XP_796740 252 27486 F178 L I Q A Y T N F S N G H T G Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LTI3 239 26400 F166 I P Q I W K N F R N K S T G Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71 98.7 89.4 N.A. 91 88.6 N.A. N.A. N.A. N.A. 67 N.A. 47.6 51 38.4 54.3
Protein Similarity: 100 76.4 100 93.9 N.A. 94.7 93.5 N.A. N.A. N.A. N.A. 83.1 N.A. 67.8 66.4 58.2 72.6
P-Site Identity: 100 13.3 100 86.6 N.A. 93.3 100 N.A. N.A. N.A. N.A. 80 N.A. 66.6 73.3 53.3 73.3
P-Site Similarity: 100 26.6 100 93.3 N.A. 93.3 100 N.A. N.A. N.A. N.A. 86.6 N.A. 66.6 86.6 60 86.6
Percent
Protein Identity: N.A. N.A. N.A. 33.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 75 42 0 0 0 0 17 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 9 0 9 0 0 0 84 9 0 100 0 % G
% His: 0 0 0 0 0 0 0 0 25 0 0 59 0 0 0 % H
% Ile: 9 34 0 17 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 17 0 0 0 0 9 0 0 0 0 % K
% Leu: 84 42 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 92 0 0 75 0 9 0 0 0 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 92 0 0 9 0 9 17 0 9 0 0 0 92 % Q
% Arg: 0 0 0 9 0 0 0 0 34 0 0 0 0 0 0 % R
% Ser: 0 9 0 0 17 0 0 0 9 0 0 25 0 0 0 % S
% Thr: 0 0 9 0 0 75 0 0 9 0 0 0 92 0 0 % T
% Val: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 25 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _