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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD3
All Species:
9.09
Human Site:
S510
Identified Species:
22.22
UniProt:
O75355
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75355
NP_001239.2
529
59105
S510
A
F
L
A
Y
L
C
S
A
T
R
R
K
R
H
Chimpanzee
Pan troglodytes
XP_001135647
529
59059
S510
A
F
L
A
Y
L
C
S
A
T
R
R
K
R
H
Rhesus Macaque
Macaca mulatta
XP_001110787
529
59036
S510
A
F
L
A
Y
L
C
S
A
S
R
K
K
R
H
Dog
Lupus familis
XP_542723
547
61253
V528
A
F
L
V
Y
L
Y
V
S
S
R
K
Q
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0L2
497
54632
L479
A
G
V
V
F
A
V
L
T
L
V
A
I
L
G
Rat
Rattus norvegicus
Q5DRK1
494
54312
L476
A
G
V
V
F
A
V
L
T
L
V
A
I
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509821
515
57743
V496
V
F
L
V
Y
L
C
V
V
S
Q
L
Q
K
T
Chicken
Gallus gallus
O93295
493
54016
L475
G
A
I
S
F
I
V
L
A
I
V
A
G
L
V
Frog
Xenopus laevis
NP_001085737
508
57031
I490
S
I
L
L
V
C
I
I
L
I
C
W
L
T
F
Zebra Danio
Brachydanio rerio
NP_001077050
497
55526
V479
G
L
L
L
L
F
S
V
L
T
I
I
T
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.9
79.8
N.A.
38.7
38.5
N.A.
71.2
41.9
40
49.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.6
89
N.A.
56.3
55.3
N.A.
82.6
58.5
58
64
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
46.6
N.A.
6.6
6.6
N.A.
33.3
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
20
20
N.A.
60
33.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
10
0
30
0
20
0
0
40
0
0
30
0
0
0
% A
% Cys:
0
0
0
0
0
10
40
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
50
0
0
30
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
20
20
0
0
0
0
0
0
0
0
0
0
10
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% H
% Ile:
0
10
10
0
0
10
10
10
0
20
10
10
20
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
20
30
10
0
% K
% Leu:
0
10
70
20
10
50
0
30
20
20
0
10
10
40
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
20
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
40
20
0
40
0
% R
% Ser:
10
0
0
10
0
0
10
30
10
30
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
20
30
0
0
10
10
20
% T
% Val:
10
0
20
40
10
0
30
30
10
0
30
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
50
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _