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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD5
All Species:
30
Human Site:
Y242
Identified Species:
60
UniProt:
O75356
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75356
NP_001240.1
428
47517
Y242
Y
K
L
Y
T
H
S
Y
L
G
F
G
L
K
A
Chimpanzee
Pan troglodytes
XP_510057
428
47543
Y242
Y
K
L
Y
T
H
S
Y
L
G
F
G
L
K
A
Rhesus Macaque
Macaca mulatta
XP_001092475
428
47501
Y242
Y
K
L
Y
T
H
S
Y
L
G
F
G
L
K
A
Dog
Lupus familis
XP_853865
428
47445
Y242
Y
K
L
Y
T
H
S
Y
L
G
F
G
L
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUZ9
427
47083
Y241
F
K
L
Y
T
H
S
Y
L
G
F
G
L
K
A
Rat
Rattus norvegicus
Q9ER31
455
49881
Y266
F
K
L
Y
S
Y
S
Y
L
G
L
G
L
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O93295
493
54016
G246
T
H
S
Y
L
C
Y
G
Q
I
Q
A
S
K
R
Frog
Xenopus laevis
NP_001089154
468
52036
Y281
Y
S
L
Y
S
H
S
Y
L
G
Y
G
L
M
S
Zebra Danio
Brachydanio rerio
XP_684862
450
50634
Y264
Y
E
L
Y
T
H
S
Y
L
G
N
G
V
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722860
464
51101
L275
F
T
H
S
Y
L
G
L
G
L
M
A
A
R
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XU84
479
53825
H241
D
I
D
F
F
G
H
H
I
R
L
F
T
H
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32621
518
56803
H288
Y
T
L
Y
Q
F
S
H
L
G
Y
G
L
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.6
92.7
N.A.
88
47
N.A.
N.A.
29.6
44
53.1
N.A.
35.1
N.A.
32.7
N.A.
Protein Similarity:
100
99.7
98.8
96.7
N.A.
93.6
61.5
N.A.
N.A.
43.6
58.7
70
N.A.
52.7
N.A.
49.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
60
N.A.
N.A.
13.3
66.6
73.3
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
N.A.
13.3
86.6
86.6
N.A.
13.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
17
9
0
50
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
25
0
0
9
9
9
0
0
0
0
42
9
0
9
0
% F
% Gly:
0
0
0
0
0
9
9
9
9
75
0
75
0
0
0
% G
% His:
0
9
9
0
0
59
9
17
0
0
0
0
0
9
9
% H
% Ile:
0
9
0
0
0
0
0
0
9
9
0
0
0
0
0
% I
% Lys:
0
50
0
0
0
0
0
0
0
0
0
0
0
59
0
% K
% Leu:
0
0
75
0
9
9
0
9
75
9
17
0
67
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
17
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
9
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
9
% R
% Ser:
0
9
9
9
17
0
75
0
0
0
0
0
9
0
25
% S
% Thr:
9
17
0
0
50
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
59
0
0
84
9
9
9
67
0
0
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _