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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PROP1 All Species: 4.55
Human Site: S57 Identified Species: 11.11
UniProt: O75360 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75360 NP_006252.2 226 24957 S57 G G G R S R F S P Q G G Q R G
Chimpanzee Pan troglodytes XP_527140 226 24901 S57 G G G R S R F S P Q G G Q R G
Rhesus Macaque Macaca mulatta XP_001096271 540 59025 A278 P L G R H H T A A S S D R P P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P97458 223 25007 P54 S G T E L G R P K L C P Q R G
Rat Rattus norvegicus Q63087 326 36886 G120 K S E L D E L G D K C D S N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q0IH87 483 53526 I207 E S E E G S D I D S E P D L P
Zebra Danio Brachydanio rerio O42250 344 37854 D139 C L S G D R N D G K N S G N S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q06453 408 43639 D73 P V S D G N S D C E A D E Y A
Honey Bee Apis mellifera XP_624630 369 40270 E137 A P T S P E S E T E V D D F A
Nematode Worm Caenorhab. elegans NP_505519 264 29343 G73 G L G G S V F G S S I A G V T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 31.2 N.A. N.A. 72.5 27.2 N.A. N.A. N.A. 24.8 26.7 N.A. 25.7 30 27.2 N.A.
Protein Similarity: 100 98.6 35 N.A. N.A. 77.8 40.7 N.A. N.A. N.A. 30.8 36.6 N.A. 34 38.4 44.3 N.A.
P-Site Identity: 100 100 13.3 N.A. N.A. 26.6 0 N.A. N.A. N.A. 0 6.6 N.A. 0 0 26.6 N.A.
P-Site Similarity: 100 100 26.6 N.A. N.A. 26.6 6.6 N.A. N.A. N.A. 0 13.3 N.A. 13.3 6.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 10 10 0 10 10 0 0 20 % A
% Cys: 10 0 0 0 0 0 0 0 10 0 20 0 0 0 0 % C
% Asp: 0 0 0 10 20 0 10 20 20 0 0 40 20 0 0 % D
% Glu: 10 0 20 20 0 20 0 10 0 20 10 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 30 0 0 0 0 0 0 10 0 % F
% Gly: 30 30 40 20 20 10 0 20 10 0 20 20 20 0 30 % G
% His: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 10 20 0 0 0 0 0 % K
% Leu: 0 30 0 10 10 0 10 0 0 10 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 10 0 0 0 10 0 0 20 0 % N
% Pro: 20 10 0 0 10 0 0 10 20 0 0 20 0 10 20 % P
% Gln: 0 0 0 0 0 0 0 0 0 20 0 0 30 0 0 % Q
% Arg: 0 0 0 30 0 30 10 0 0 0 0 0 10 30 0 % R
% Ser: 10 20 20 10 30 10 20 20 10 30 10 10 10 0 10 % S
% Thr: 0 0 20 0 0 0 10 0 10 0 0 0 0 0 10 % T
% Val: 0 10 0 0 0 10 0 0 0 0 10 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _