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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PITX3
All Species:
19.39
Human Site:
S266
Identified Species:
47.41
UniProt:
O75364
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75364
NP_005020.1
302
31832
S266
P
C
N
S
S
L
A
S
L
R
L
K
A
K
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001091288
325
35835
L289
R
D
T
C
N
S
S
L
A
S
L
R
L
K
A
Dog
Lupus familis
XP_543986
315
33074
S279
P
C
N
S
S
L
A
S
L
R
L
K
A
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35160
302
31696
S266
P
C
N
S
S
L
A
S
L
R
L
K
A
K
Q
Rat
Rattus norvegicus
P81062
302
31710
S266
P
C
N
S
S
L
A
S
L
R
L
K
A
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O93385
333
36539
L297
R
D
T
C
N
S
S
L
A
S
L
R
L
K
A
Frog
Xenopus laevis
Q9I8K3
292
32567
L256
R
D
T
C
N
S
S
L
A
S
L
R
L
K
A
Zebra Danio
Brachydanio rerio
Q9W5Z2
314
35169
L278
R
D
T
C
N
S
S
L
A
S
L
R
L
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18400
509
53198
T464
S
M
S
S
S
I
A
T
L
R
L
K
A
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52906
323
36184
T266
P
M
S
P
T
T
A
T
S
R
F
S
T
A
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
55
93
N.A.
98.3
98
N.A.
N.A.
53.4
68.5
55
N.A.
29.2
N.A.
32.5
N.A.
Protein Similarity:
100
N.A.
64.6
93
N.A.
98.3
98.3
N.A.
N.A.
63
79.4
66.8
N.A.
37.3
N.A.
46.7
N.A.
P-Site Identity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
N.A.
13.3
13.3
13.3
N.A.
66.6
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
33.3
100
N.A.
100
100
N.A.
N.A.
33.3
33.3
33.3
N.A.
86.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
60
0
40
0
0
0
50
10
50
% A
% Cys:
0
40
0
40
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
50
0
90
0
% K
% Leu:
0
0
0
0
0
40
0
40
50
0
90
0
40
0
0
% L
% Met:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
40
0
40
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% Q
% Arg:
40
0
0
0
0
0
0
0
0
60
0
40
0
0
0
% R
% Ser:
10
0
20
50
50
40
40
40
10
40
0
10
0
0
0
% S
% Thr:
0
0
40
0
10
10
0
20
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _