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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AVIL
All Species:
22.12
Human Site:
S456
Identified Species:
44.24
UniProt:
O75366
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75366
NP_006567.2
819
92028
S456
S
Q
D
E
L
A
A
S
A
Y
Q
A
V
E
V
Chimpanzee
Pan troglodytes
XP_509177
819
92037
S456
S
Q
D
E
L
A
A
S
A
Y
Q
A
V
E
V
Rhesus Macaque
Macaca mulatta
XP_001101627
837
93554
S474
S
Q
D
E
L
A
A
S
A
Y
Q
A
V
E
V
Dog
Lupus familis
XP_531652
817
91548
S457
S
K
D
E
L
A
A
S
A
Y
Q
A
V
E
V
Cat
Felis silvestris
Mouse
Mus musculus
O88398
819
92168
S456
S
R
D
E
L
A
A
S
A
Y
R
A
V
E
V
Rat
Rattus norvegicus
Q68FP1
780
86049
A461
N
K
V
L
V
D
P
A
T
Y
G
Q
F
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02640
826
92461
S459
S
T
D
E
L
A
A
S
A
Y
Q
A
V
F
L
Frog
Xenopus laevis
P14885
417
46006
Q103
V
L
E
S
H
Y
G
Q
F
Y
G
G
D
S
Y
Zebra Danio
Brachydanio rerio
NP_001035455
811
90971
C455
S
Q
D
E
V
T
A
C
A
Y
H
A
V
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07171
798
88356
V476
P
G
S
D
E
I
V
V
S
T
V
P
F
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107669
831
93189
A467
S
K
D
E
Q
G
A
A
A
I
L
T
T
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81645
966
106448
A454
N
Q
E
D
Q
E
T
A
V
R
L
A
S
T
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
93.3
88.2
N.A.
89.1
42.7
N.A.
N.A.
62.9
26.7
63.7
N.A.
33.9
N.A.
N.A.
44.2
Protein Similarity:
100
99.3
95.2
93.5
N.A.
94.5
56.5
N.A.
N.A.
77.2
35.4
78.5
N.A.
50.9
N.A.
N.A.
64.3
P-Site Identity:
100
100
100
93.3
N.A.
86.6
6.6
N.A.
N.A.
80
6.6
66.6
N.A.
0
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
N.A.
86.6
13.3
73.3
N.A.
20
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
50
67
25
67
0
0
67
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
67
17
0
9
0
0
0
0
0
0
9
9
0
% D
% Glu:
0
0
17
67
9
9
0
0
0
0
0
0
0
42
9
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
17
9
0
% F
% Gly:
0
9
0
0
0
9
9
0
0
0
17
9
0
0
9
% G
% His:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
25
0
0
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
0
9
0
9
50
0
0
0
0
0
17
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% M
% Asn:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% P
% Gln:
0
42
0
0
17
0
0
9
0
0
42
9
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
9
9
0
0
0
0
% R
% Ser:
67
0
9
9
0
0
0
50
9
0
0
0
9
9
0
% S
% Thr:
0
9
0
0
0
9
9
0
9
9
0
9
9
17
0
% T
% Val:
9
0
9
0
17
0
9
9
9
0
9
0
59
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
75
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _