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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AVIL
All Species:
29.39
Human Site:
S501
Identified Species:
58.79
UniProt:
O75366
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75366
NP_006567.2
819
92028
S501
V
I
F
E
G
G
T
S
R
K
G
N
A
E
P
Chimpanzee
Pan troglodytes
XP_509177
819
92037
S501
V
I
F
E
G
G
T
S
R
K
G
N
A
E
P
Rhesus Macaque
Macaca mulatta
XP_001101627
837
93554
S519
V
I
F
E
G
G
T
S
R
K
G
N
A
E
P
Dog
Lupus familis
XP_531652
817
91548
S502
V
I
F
E
G
G
T
S
R
T
G
N
A
E
P
Cat
Felis silvestris
Mouse
Mus musculus
O88398
819
92168
S501
V
I
Y
E
G
G
T
S
R
K
G
N
E
E
P
Rat
Rattus norvegicus
Q68FP1
780
86049
S496
Y
N
W
Q
G
A
Q
S
T
Q
D
E
V
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02640
826
92461
S504
V
V
Y
E
N
G
S
S
R
A
G
G
T
E
P
Frog
Xenopus laevis
P14885
417
46006
K136
W
Q
G
D
D
S
T
K
D
E
I
T
A
S
A
Zebra Danio
Brachydanio rerio
NP_001035455
811
90971
S500
V
I
Y
E
G
G
T
S
R
K
G
P
V
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07171
798
88356
T510
N
G
D
T
G
S
L
T
Y
V
W
H
G
V
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107669
831
93189
C513
I
H
L
A
G
R
S
C
G
F
K
N
Q
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81645
966
106448
S499
V
L
K
G
G
L
S
S
G
Y
K
N
S
M
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
93.3
88.2
N.A.
89.1
42.7
N.A.
N.A.
62.9
26.7
63.7
N.A.
33.9
N.A.
N.A.
44.2
Protein Similarity:
100
99.3
95.2
93.5
N.A.
94.5
56.5
N.A.
N.A.
77.2
35.4
78.5
N.A.
50.9
N.A.
N.A.
64.3
P-Site Identity:
100
100
100
93.3
N.A.
86.6
13.3
N.A.
N.A.
53.3
13.3
80
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
N.A.
73.3
26.6
86.6
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
0
0
9
0
0
42
9
25
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
9
0
0
0
9
0
9
0
0
0
0
% D
% Glu:
0
0
0
59
0
0
0
0
0
9
0
9
9
59
0
% E
% Phe:
0
0
34
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
9
9
9
84
59
0
0
17
0
59
9
9
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
9
50
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
9
0
42
17
0
0
0
9
% K
% Leu:
0
9
9
0
0
9
9
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
9
0
0
9
0
0
0
0
0
0
59
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
59
% P
% Gln:
0
9
0
9
0
0
9
0
0
9
0
0
9
9
0
% Q
% Arg:
0
0
0
0
0
9
0
0
59
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
17
25
75
0
0
0
0
9
9
0
% S
% Thr:
0
0
0
9
0
0
59
9
9
9
0
9
9
0
9
% T
% Val:
67
9
0
0
0
0
0
0
0
9
0
0
17
9
0
% V
% Trp:
9
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
9
0
25
0
0
0
0
0
9
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _