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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AVIL
All Species:
19.39
Human Site:
S578
Identified Species:
38.79
UniProt:
O75366
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75366
NP_006567.2
819
92028
S578
A
S
L
L
C
D
G
S
E
N
T
V
A
E
G
Chimpanzee
Pan troglodytes
XP_509177
819
92037
S578
A
S
L
L
C
D
G
S
E
N
T
V
A
E
G
Rhesus Macaque
Macaca mulatta
XP_001101627
837
93554
S596
A
S
L
L
C
D
G
S
E
N
T
V
A
E
G
Dog
Lupus familis
XP_531652
817
91548
T579
A
S
F
L
C
E
G
T
E
D
T
V
A
E
G
Cat
Felis silvestris
Mouse
Mus musculus
O88398
819
92168
N578
V
D
L
L
C
D
G
N
A
D
T
V
A
E
G
Rat
Rattus norvegicus
Q68FP1
780
86049
V566
A
S
T
R
L
F
Q
V
R
A
S
S
S
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02640
826
92461
E581
A
D
I
I
S
K
T
E
K
P
V
V
A
E
G
Frog
Xenopus laevis
P14885
417
46006
T206
V
R
L
F
Q
V
R
T
S
S
S
G
F
S
R
Zebra Danio
Brachydanio rerio
NP_001035455
811
90971
E577
S
V
I
M
G
R
S
E
Q
V
M
A
E
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07171
798
88356
S581
R
I
R
G
T
V
E
S
D
V
H
A
S
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107669
831
93189
S594
A
K
V
L
E
P
K
S
A
Y
T
L
V
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81645
966
106448
T586
A
E
F
L
K
P
G
T
T
I
K
H
A
K
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
93.3
88.2
N.A.
89.1
42.7
N.A.
N.A.
62.9
26.7
63.7
N.A.
33.9
N.A.
N.A.
44.2
Protein Similarity:
100
99.3
95.2
93.5
N.A.
94.5
56.5
N.A.
N.A.
77.2
35.4
78.5
N.A.
50.9
N.A.
N.A.
64.3
P-Site Identity:
100
100
100
73.3
N.A.
66.6
13.3
N.A.
N.A.
33.3
6.6
0
N.A.
13.3
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
80
26.6
N.A.
N.A.
53.3
26.6
26.6
N.A.
26.6
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
0
0
0
0
0
17
9
0
17
59
0
9
% A
% Cys:
0
0
0
0
42
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
0
34
0
0
9
17
0
0
0
0
0
% D
% Glu:
0
9
0
0
9
9
9
17
34
0
0
0
9
59
17
% E
% Phe:
0
0
17
9
0
9
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
9
9
0
50
0
0
0
0
9
0
17
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% H
% Ile:
0
9
17
9
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
9
0
0
9
9
9
0
9
0
9
0
0
9
0
% K
% Leu:
0
0
42
59
9
0
0
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
25
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
17
0
0
0
9
0
0
0
9
0
% P
% Gln:
0
0
0
0
9
0
9
0
9
0
0
0
0
0
9
% Q
% Arg:
9
9
9
9
0
9
9
0
9
0
0
0
0
0
9
% R
% Ser:
9
42
0
0
9
0
9
42
9
9
17
9
17
9
0
% S
% Thr:
0
0
9
0
9
0
9
25
9
0
50
0
0
0
0
% T
% Val:
17
9
9
0
0
17
0
9
0
17
9
50
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _