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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AVIL All Species: 23.03
Human Site: S684 Identified Species: 46.06
UniProt: O75366 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75366 NP_006567.2 819 92028 S684 Q Y L H T H P S G R D P D T P
Chimpanzee Pan troglodytes XP_509177 819 92037 S684 Q Y L H T H P S G R D P D T P
Rhesus Macaque Macaca mulatta XP_001101627 837 93554 S702 Q Y L L T H P S G R D P D T P
Dog Lupus familis XP_531652 817 91548 S685 E Y L H T H P S G R D A D T A
Cat Felis silvestris
Mouse Mus musculus O88398 819 92168 S684 E Y L V T H P S G R D P D T P
Rat Rattus norvegicus Q68FP1 780 86049 C670 H P P R L F A C S N R I G R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P02640 826 92461 G687 E Y L R S H P G S R D L D T P
Frog Xenopus laevis P14885 417 46006 N309 P R L F A C S N K T G R F I I
Zebra Danio Brachydanio rerio NP_001035455 811 90971 G682 E Y L R T H P G S R D P D T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07171 798 88356 S685 L F H C H L S S G G F L K V E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001107669 831 93189 S701 E Y L M T D P S G R D P D S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81645 966 106448 S691 R Y I N L A G S L E G L S P K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 93.3 88.2 N.A. 89.1 42.7 N.A. N.A. 62.9 26.7 63.7 N.A. 33.9 N.A. N.A. 44.2
Protein Similarity: 100 99.3 95.2 93.5 N.A. 94.5 56.5 N.A. N.A. 77.2 35.4 78.5 N.A. 50.9 N.A. N.A. 64.3
P-Site Identity: 100 100 93.3 80 N.A. 86.6 0 N.A. N.A. 60 6.6 73.3 N.A. 13.3 N.A. N.A. 66.6
P-Site Similarity: 100 100 93.3 86.6 N.A. 93.3 0 N.A. N.A. 73.3 13.3 80 N.A. 20 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 31.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 9 9 0 0 0 0 9 0 0 9 % A
% Cys: 0 0 0 9 0 9 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 0 0 67 0 67 0 0 % D
% Glu: 42 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % E
% Phe: 0 9 0 9 0 9 0 0 0 0 9 0 9 0 9 % F
% Gly: 0 0 0 0 0 0 9 17 59 9 17 0 9 0 0 % G
% His: 9 0 9 25 9 59 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 0 9 0 9 9 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 9 % K
% Leu: 9 0 75 9 17 9 0 0 9 0 0 25 0 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 9 0 9 0 0 0 0 0 % N
% Pro: 9 9 9 0 0 0 67 0 0 0 0 50 0 9 50 % P
% Gln: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 9 0 25 0 0 0 0 0 67 9 9 0 9 0 % R
% Ser: 0 0 0 0 9 0 17 67 25 0 0 0 9 9 0 % S
% Thr: 0 0 0 0 59 0 0 0 0 9 0 0 0 59 9 % T
% Val: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _