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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AVIL
All Species:
27.88
Human Site:
Y552
Identified Species:
55.76
UniProt:
O75366
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75366
NP_006567.2
819
92028
Y552
L
R
T
Q
A
E
H
Y
L
W
Y
G
K
G
S
Chimpanzee
Pan troglodytes
XP_509177
819
92037
Y552
L
R
T
Q
A
E
H
Y
L
W
Y
G
K
G
S
Rhesus Macaque
Macaca mulatta
XP_001101627
837
93554
Y570
L
R
T
Q
A
E
H
Y
L
W
Y
G
K
G
S
Dog
Lupus familis
XP_531652
817
91548
Y553
L
R
T
Q
G
E
H
Y
L
W
Y
G
K
G
S
Cat
Felis silvestris
Mouse
Mus musculus
O88398
819
92168
Y552
L
R
T
Q
A
E
H
Y
L
W
Y
G
K
G
S
Rat
Rattus norvegicus
Q68FP1
780
86049
K540
L
M
S
L
F
G
G
K
P
M
I
I
Y
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02640
826
92461
Y555
L
K
T
P
S
S
C
Y
L
W
Y
G
K
G
C
Frog
Xenopus laevis
P14885
417
46006
M180
S
L
F
G
G
K
P
M
I
I
Y
K
G
G
T
Zebra Danio
Brachydanio rerio
NP_001035455
811
90971
Y551
L
K
S
Q
S
G
V
Y
L
W
Y
G
K
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07171
798
88356
F555
P
R
H
F
Y
K
I
F
K
G
K
L
L
T
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107669
831
93189
Y568
I
K
G
P
K
Q
L
Y
I
W
A
G
K
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81645
966
106448
F560
L
Q
S
G
T
S
M
F
L
W
V
G
N
H
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
93.3
88.2
N.A.
89.1
42.7
N.A.
N.A.
62.9
26.7
63.7
N.A.
33.9
N.A.
N.A.
44.2
Protein Similarity:
100
99.3
95.2
93.5
N.A.
94.5
56.5
N.A.
N.A.
77.2
35.4
78.5
N.A.
50.9
N.A.
N.A.
64.3
P-Site Identity:
100
100
100
93.3
N.A.
100
6.6
N.A.
N.A.
60
13.3
66.6
N.A.
13.3
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
13.3
N.A.
N.A.
73.3
33.3
86.6
N.A.
26.6
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
34
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
9
9
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
17
17
17
9
0
0
9
0
75
9
75
17
% G
% His:
0
0
9
0
0
0
42
0
0
0
0
0
0
9
0
% H
% Ile:
9
0
0
0
0
0
9
0
17
9
9
9
0
0
0
% I
% Lys:
0
25
0
0
9
17
0
9
9
0
9
9
67
9
0
% K
% Leu:
75
9
0
9
0
0
9
0
67
0
0
9
9
0
0
% L
% Met:
0
9
0
0
0
0
9
9
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
9
0
0
17
0
0
9
0
9
0
0
0
0
0
0
% P
% Gln:
0
9
0
50
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
25
0
17
17
0
0
0
0
0
0
0
0
67
% S
% Thr:
0
0
50
0
9
0
0
0
0
0
0
0
0
9
9
% T
% Val:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
67
0
0
67
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _