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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SH3BGRL All Species: 32.42
Human Site: S11 Identified Species: 64.85
UniProt: O75368 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75368 NP_003013.1 114 12774 S11 R V Y I A S S S G S T A I K K
Chimpanzee Pan troglodytes XP_001145030 105 11772 S11 R V Y I A S S S G S T A I K K
Rhesus Macaque Macaca mulatta XP_001101367 133 15151 G30 T R Q H P S T G H L H Q I K K
Dog Lupus familis XP_549106 104 11762 L17 Q Q D V L G F L E A N K I G F
Cat Felis silvestris
Mouse Mus musculus Q9JJU8 114 12793 S11 R V Y I A S S S G S T A I K K
Rat Rattus norvegicus XP_217566 114 12782 S11 H V Y I A S S S G S T A I K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519197 122 13752 A19 R V F V S S W A G N A A I K K
Chicken Gallus gallus NP_001012592 114 12777 S11 K V Y I A S S S G S T A I K K
Frog Xenopus laevis Q3KPU0 106 12454 S11 R V F L A S S S S S V T I K K
Zebra Danio Brachydanio rerio Q6GMK7 105 12112 S11 R V Y I A S S S G S V A V K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NFP5 158 17470 S11 K V Y V S G M S G N K E V K K
Honey Bee Apis mellifera XP_624305 177 20052 S11 K I Y I S G I S G N K E V K K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.1 80.4 85.9 N.A. 94.7 95.6 N.A. 78.6 86.8 55.2 53.5 N.A. 30.3 26.5 N.A. N.A.
Protein Similarity: 100 92.1 82.7 87.7 N.A. 96.4 96.4 N.A. 87.6 94.7 71 69.3 N.A. 45.5 37.8 N.A. N.A.
P-Site Identity: 100 100 26.6 6.6 N.A. 100 93.3 N.A. 53.3 93.3 66.6 86.6 N.A. 40 40 N.A. N.A.
P-Site Similarity: 100 100 33.3 26.6 N.A. 100 93.3 N.A. 86.6 100 80 93.3 N.A. 73.3 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 59 0 0 9 0 9 9 59 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 9 0 0 17 0 0 0 % E
% Phe: 0 0 17 0 0 0 9 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 25 0 9 75 0 0 0 0 9 0 % G
% His: 9 0 0 9 0 0 0 0 9 0 9 0 0 0 0 % H
% Ile: 0 9 0 59 0 0 9 0 0 0 0 0 75 0 0 % I
% Lys: 25 0 0 0 0 0 0 0 0 0 17 9 0 92 92 % K
% Leu: 0 0 0 9 9 0 0 9 0 9 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 25 9 0 0 0 0 % N
% Pro: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 9 9 0 0 0 0 0 0 0 0 9 0 0 0 % Q
% Arg: 50 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 25 75 59 75 9 59 0 0 0 0 0 % S
% Thr: 9 0 0 0 0 0 9 0 0 0 42 9 0 0 0 % T
% Val: 0 75 0 25 0 0 0 0 0 0 17 0 25 0 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _